Levothyroxine sodium side effect: Gout
Summary:
We study 115,376 people who have side effects when taking Levothyroxine sodium, Gout is reported. Gout is reported especially by people who are female, 60+ old, have been taking the drug for < 1 month, also take Allopurinol and have High blood pressure.
The phase IV clinical study analyzes which people take Levothyroxine sodium and have Gout. It is created by eHealthMe based on reports from the FDA, and is updated regularly.
eHealthMe is trusted by doctors and researchers. Our phase IV clinical studies have been referenced on 700+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Check your drugs now, it's FREE >>>
115,376 people reported to have side effects when taking Levothyroxine sodium.
Among them, 260 people (0.23%) have Gout.
What is Levothyroxine sodium?
Levothyroxine sodium has active ingredients of levothyroxine sodium. It is used in hypothyroidism. Currently, eHealthMe is studying from 122,098 Levothyroxine sodium users.
What is Gout?
Gout (uric acid crystals building up in the body) is found to be associated with 1,083 drugs and 1,301 conditions by eHealthMe. Currently, we are studying 51,836 people who have Gout.
Number of Levothyroxine sodium and Gout reports submitted per year:
Time on Levothyroxine sodium when people have Gout *:
Gender of people who have Gout when taking Levothyroxine sodium*:
Age of people who have Gout when taking Levothyroxine sodium *:
Common drugs people take besides Levothyroxine sodium *:
Common side effects people have besides Gout *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Levothyroxine sodium and have Gout?
Check whether Gout is associated with a drug or a conditionWhat are phase IV trials?
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world, as opposed to phase I-III trials that are used in drug approval. With real-world big data and AI/ML algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public.
Why use real-world data?
New drugs have to go through a series (phase I-III) of clinical trials before they are approved by the FDA. These clinical trials have guidelines about who can participate. The guidelines ensure that only a selected set of people are chosen due to time and costs. When the drugs are approved and released in the market to a much bigger and ever-changing public, it is not uncommon for drugs to behave differently in the real world than in (phase I-III) clinical trials.
During the past 30 years, special regulatory programs are available to the FDA including Fast Track (1988, in statute 1997), Priority Review (1992), Accelerated Approval (1992), and Breakthrough Therapy designation (2012). These programs potentially contribute to the variability of the quantity and quality of evidence supporting recent drug approvals.
All these suggest an ongoing need for continued evaluation of therapeutic safety and efficacy after drug approvals. The 21st Century Cures Act, passed in 2016, places additional focus on the use of real-world data to support regulatory decision making. The FDA has started to use real-world data to monitor postmarket safety and adverse events, and payers to support value-based payment program.
How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Gout and when was it recovered:
Levothyroxine sodium side effects by duration, gender and age:
- Levothyroxine sodium side effects (122,098 reports)
Common Levothyroxine sodium side effects:
- Fatigue (feeling of tiredness): 9,438 reports
- Diarrhea: 7,187 reports
- Weakness: 6,636 reports
- Breathing difficulty: 6,530 reports
- Headache (pain in head): 6,134 reports
- Pain: 6,121 reports
- Dizziness: 5,913 reports
- Drug ineffective: 5,863 reports
- High blood pressure: 5,317 reports
- Rashes (redness): 5,020 reports
- Nausea and vomiting: 5,011 reports
- Malaise (a feeling of general discomfort or uneasiness): 4,443 reports
- Joint pain: 4,330 reports
- Fever: 3,987 reports
- Hypotension (abnormally low blood pressure): 3,773 reports
- Pneumonia: 3,720 reports
- Chest pain: 3,660 reports
- Stress and anxiety: 3,609 reports
- Constipation: 3,580 reports
- Weight decreased: 3,335 reports
- Itching: 3,198 reports
- Insomnia (sleeplessness): 3,011 reports
- Urinary tract infection: 2,921 reports
- Cough: 2,870 reports
- Oedema peripheral (superficial swelling): 2,793 reports
- Depression: 2,727 reports
- Back pain: 2,722 reports
- Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 2,715 reports
- Abdominal pain: 2,708 reports
- Weight increased: 2,597 reports
- Death: 2,573 reports
- Thrombocytopenia (decrease of platelets in blood): 2,509 reports
- Dehydration (dryness resulting from the removal of water): 2,444 reports
- Hair loss: 2,339 reports
- Memory loss: 2,280 reports
- Drowsiness: 2,278 reports
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2,151 reports
- Arrhythmias (irregular heartbeat): 2,032 reports
- Muscle spasms (muscle contraction): 1,981 reports
- Muscle aches (muscle pain): 1,949 reports
- Tremor (trembling or shaking movements in one or more parts of your body): 1,928 reports
- Heart palpitations (feelings or sensations that your heart is pounding or racing): 1,924 reports
- Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1,830 reports
- Asthma: 1,635 reports
- Acute kidney failure: 1,596 reports
- Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1,593 reports
- Head injury: 1,586 reports
- Sinusitis (inflammation of sinus): 1,565 reports
- Fainting (loss of consciousness and postural tone): 1,511 reports
- Hyperhidrosis (abnormally increased sweating): 1,494 reports
- Heart attack: 1,475 reports
- Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 1,385 reports
- Joint swelling: 1,367 reports
- Chills (felling of cold): 1,309 reports
Browse all side effects of Levothyroxine sodium:
a b c d e f g h i j k l m n o p q r s t u v w x y zGout treatments and more:
- Gout (51,836 reports)
Common drugs associated with Gout:
- Allopurinol: 2,716 reports
- Lopurin: 2,716 reports
- Aspirin: 1,860 reports
- Prednisone: 1,656 reports
- Furosemide: 1,355 reports
- Lisinopril: 1,021 reports
- Amlodipine: 987 reports
- Lasix: 984 reports
- Colchicine: 928 reports
- Metformin: 927 reports
- Revlimid: 855 reports
- Pantoprazole: 790 reports
- Gabapentin: 782 reports
- Humira: 776 reports
- Lipitor: 700 reports
- Vitamin d: 691 reports
- Simvastatin: 673 reports
- Omeprazole: 655 reports
- Uloric: 628 reports
- Vioxx: 622 reports
- Tylenol: 599 reports
- Synthroid: 594 reports
- Methotrexate: 573 reports
- Eliquis: 557 reports
- Coumadin: 547 reports
- Zide: 535 reports
- Hydrochlorothiazide: 534 reports
- Atenolol: 528 reports
- Fosamax: 512 reports
- Sandostatin: 489 reports
- Plavix: 488 reports
- Crestor: 478 reports
- Entresto: 456 reports
- Norvasc: 427 reports
- Albuterol: 426 reports
- Spironolactone: 421 reports
- Losartan: 421 reports
- Enbrel: 416 reports
- Nexium: 416 reports
- Tramadol: 415 reports
- Sandostatin lar: 415 reports
- Jakafi: 414 reports
- Lantus: 398 reports
- Spiriva: 395 reports
- Krystexxa: 383 reports
- Vitamin d3: 375 reports
- Zometa: 370 reports
- Prilosec: 366 reports
- Ramipril: 362 reports
- Calcium: 358 reports
- Diovan: 357 reports
- Ibuprofen: 353 reports
- Ibu: 353 reports
- Profen: 353 reports
- Protonix: 352 reports
- Metoprolol tartrate: 348 reports
- Digoxin: 347 reports
- Celebrex: 337 reports
- Carvedilol: 336 reports
- Opsumit: 335 reports
- Magnesium: 331 reports
- Lyrica: 324 reports
- Singulair: 320 reports
- Fish oil: 318 reports
- Zocor: 306 reports
- Imbruvica: 300 reports
- Vitamin b12: 293 reports
- Xarelto: 292 reports
- Acetaminophen: 292 reports
- Vitamins: 291 reports
- Xeljanz: 287 reports
- Coreg: 283 reports
- Indomethacin: 271 reports
- Acetylsalicylic acid: 270 reports
- Folic acid: 268 reports
- Benadryl: 260 reports
- Levothyroxine sodium: 260 reports
- Colcrys: 258 reports
- Finasteride: 256 reports
- Humalog: 255 reports
- Oxycodone: 254 reports
- Cosentyx: 253 reports
- Symbicort: 253 reports
- Metoprolol succinate: 249 reports
- Tamsulosin: 247 reports
- Januvia: 241 reports
- Potassium: 240 reports
- Warfarin sodium: 239 reports
- Niaspan: 236 reports
- Wellbutrin: 233 reports
- Flomax: 232 reports
- Glipizide: 229 reports
- Xanax: 228 reports
- Hydramine: 225 reports
- Diphen: 225 reports
- Alendronate sodium: 220 reports
- Dexamethasone: 217 reports
- Ambien: 214 reports
- Torsemide: 212 reports
- Zantac: 211 reports
Common conditions associated with Gout:
- High blood pressure: 1,671 reports
- Rheumatoid arthritis: 1,117 reports
- High blood cholesterol: 974 reports
- Multiple myeloma: 891 reports
- Primary pulmonary hypertension: 834 reports
- Pain: 689 reports
- Psoriasis: 584 reports
- Osteoporosis: 580 reports
- Diabetes: 536 reports
- Type 2 diabetes: 421 reports
- Gastroesophageal reflux disease: 388 reports
- Crohn's disease: 357 reports
- Multiple sclerosis: 325 reports
- Asthma: 324 reports
- Primary myelofibrosis: 319 reports
- Depression: 312 reports
- Atrial fibrillation/flutter: 286 reports
- Arthritis: 267 reports
- Renal cell carcinoma: 186 reports
- Stress and anxiety: 183 reports
- Joint pain: 177 reports
- Prostate cancer: 174 reports
- Carcinoid tumor: 173 reports
- Hepatitis c: 171 reports
- Hypothyroidism: 170 reports
- Blood pressure management: 168 reports
- Stroke: 151 reports
- Chronic obstructive pulmonary disease: 149 reports
- Ulcerative colitis: 143 reports
- Preventive health care: 141 reports
- Thyroid diseases: 138 reports
- Hiv infection: 128 reports
- Osteoarthritis: 127 reports
- Back pain: 126 reports
- Sleep disorder: 119 reports
- Narcolepsy: 117 reports
- Kidney transplant: 110 reports
- Insomnia: 108 reports
- Fluid retention: 105 reports
- Constipation: 103 reports
- Ankylosing spondylitis: 99 reports
- Idiopathic pulmonary fibrosis: 93 reports
- Neuroendocrine tumor: 86 reports
- Acromegaly: 81 reports
- Diarrhea: 80 reports
- Muscle spasms: 76 reports
- Arrhythmias: 75 reports
- Pneumonia: 70 reports
- Breathing difficulty: 69 reports
- Gastric ulcer: 63 reports
- Chest pain: 62 reports
- Hyperkalemia: 60 reports
- Chronic kidney disease: 59 reports
- Coronary heart disease: 57 reports
- Bipolar disorder: 56 reports
- Breast cancer: 55 reports
- Heart transplant: 51 reports
- Neuralgia: 50 reports
All the conditions that are associated with Gout:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on levothyroxine sodium (the active ingredients of Levothyroxine sodium) and Levothyroxine sodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
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With real-world medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to access and run their own phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
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