PowerPoint presentations, Excel documents, Web pages, and videos posted on federal websites must meet the requirements of the 1998 amendment to Section 508 of the Rehabilitation Act. Doing so ensures that these materials are accessible to a wide range of people with disabilities, including visual, auditory, sensory, and motor impairments. These individuals use assistive technology to help them understand electronic information--for example, screen readers and text-to-speech software interpret words on the page and translate them to a computerized voice that reads the information. Accessible products work hand in hand with assistive technology. However, accessibility requirements are broad and lack step-by-step recommendations to walk the reader through the process. There is no "magic bullet" software that creates compliant files at the press of a button, so accessibility usually involves setting up files from the get-go in a structured and systematic way by using built-in features of the native software application. This is especially important with large, multi-author files, which may have complex production requirements and deadlines. For guidelines on setting up accessible templates, go to http://www.hhs.gov/web/508/accessiblefiles/index.html. The goal of this guide is to offer tips and tools for those who have a basic understanding of 508 compliance to help ease the process and reduce headaches and delays.