Rachel Andrew presented on CSS Grid Layout and Flexbox at Smashing Conf SF. She began by explaining the differences between Grid and Flexbox - Grid is for two-dimensional layout while Flexbox is for one-dimensional. She demonstrated examples of layouts using Grid and why it may be preferable to Flexbox in certain cases. Rachel then covered using Grid in production, responsive design with Grid, fallback options for older browsers, and ways for developers to encourage browser vendors to support new features. She provided several resources for learning more about Grid.