The house is located in the historical center, just along the ancient Via Francigena, the way leading from France to Rome since the Middle Ages. Nearby this ancient junction in 1283 was born the hospital for travelers, called "Donna Nobile" from which it takes its name.
The property has an enviable position being 80m from the main road and 200m from the main attractions of the town the Convent of St. Agostino with frescoes by Benozzo Gozzoli, the church of San Jacopo founded by the Knights Templar, Piazza della Cisterna, and Piazza del Duomo with the Town Hall, the "Pharmacy of Santa Fina" Museum, the Art Gallery, the Museum of Torture and many others.