Research on Efficacy of Homoeopathy

ABSTRACTSOFDIFFERENTPUBLISHEDRESEARCHRELATEDTOHOMOEOPATHYMEDICAL
SCIENCE;Asteptoshowtheefficacyofhomoeopathybyvariousscholars.By:Dr.AnkitSrivastava
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Contents:
1. Studies on Human……………………………2-39.
2. Studies on Animal…………………………....40-54.
3. Studies on Plant……………………………...55-57.
4. In Vitro Studies……………………………...58-64.

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STUDIES ON HUMAN:
1.) Albertini H, Goldberg W, Sanguy B, Toulza CL. Homeopathic treatment of
dental neuralgia by Arnica and Hypericum. Journal of the American Institute
of Homeopathy, 1985, 126-129. Carried out at the Faculty of Medicine of
Marseilles, this placebo controlled study was designed to determine the
effectiveness of Arnica 7C and Hypericum 15C for people suffering from dental
neuralgia. 60 people received either 4 pilules of Arnica alternated with 4 pilules
of Hypericum every 4 hours or placebo administered in the same way. Pain
levels were assessed over 3 days from the beginning of the trial. From this
assessment it was found that 12 of the 30 people who received the placebo had
a positive response to this intervention, and 23 of the 30 people given the
homeopathic medicines responded positively to these.
2.)Alibeu JP, Jobert J. Aconite in Post-Operative Pain and Agitation in
Children, Paediatric, 1990, 45, 7-8, 465-6: In this double blind placebo
controlled trial, 50 children suffering from post-operative pain and agitation
were given either Aconite or placebo. The effects of Aconite were significantly
better than placebo.
3.)Ammerschlager H., Klein P., Weiser M., Oberbaum M. Treatment of
inflammatory diseases of the upper respiratory tract - comparison of a
homeopathic complex remedy with xylometazoline. Forsch
Komplementarmed Klass Naturheilkd. 2005, Feb, 12, 1,:24-31: In a multi-
centre, controlled, cohort study, 739 people suffering from rhinitis or sinusitis
were given either xylometazoline (a drug commonly used for nasal congestion,
sinusitis and hay fever) or a homeopathic combination. Both forms of therapy
provided similarly effective results.
4.) Baars EW, De Bruin A. The effect of Gencydo injections on hay fever
symptoms: a therapeutic causality report. Journal of Alternative and
Complementary Medicine 2005 Oct,11, 5, 863-9. In this study, 13 Dutch
medical practitioners submitted patients (who between them had a mean history
of hay fever of 9 years), for therapy involving injections of a combination
homeopathic product. All but 1 patient were given the medication before the
onset of the hay fever season and all were given it during the hay fever season.

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Of these 13, during the course of the trial 9 people found no increase in nasal and
non-nasal hay fever symptoms when the hay fever season began or during it and
only 1 of the 13 felt compelled to use conventional hay fever medication.
5.) Baduluci S, Chirulescu Z, Chirila P, Rosca A. Zinc: Immunoglobin
Relationship in Patients with Cirrhosis of the Liver Before and After
treatment with Zincum metallicum 5C. International Research Group on Very
Low Dose and High Dilution Effects, 1993 Giri Meeting, British Homoeopathic
Journal, April, 1994, 83, 84-100. 10 people suffering from Zinc deficiency as
determined by atomic absorption spectrophotometry were treated with Zincum
metallicum 5C. Analysis following this treatment showed a substantial
improvement in zinc levels.
6.) Banerjee A, Chakrabarty SB, Karmakar SR, Chakrabarty A, Biswas SJ, Haque
S, Das D, Paul S, Mandal B, Naoual B, Belon P, Khuda-Bukhsh AR. Can
Homeopathy bring additional benefits to Thalassemic Patients on
Hydroxyurea Therapy? Encouraging Results of a Preliminary Study.
Evidence Based Complementary and Alternative Medicine. 2010 March; 7(1):
129–136. In this observational study, 38 people suffering from thalassaemia who
were taking hydroxyurea, were allowed to continue their use of hydroxyurea but
were given one of several homeopathic medicines. The effects of this additional
treatment were compared to the outcomes of another 38 people suffering from
thalassaemia who used hydroxyurea alone, assessed immediately before and at 3
months after starting the homeopathic treatment. Of a range of haematological
and clinical parameters, those people using the combined treatment showed an
increase in levels of foetal haemoglobin over those on hydroxyurea alone, along
with a reduction in serum ferritin. Where splenomegaly was present, a significant
reduction in this was noted in those on the combined therapy and this group also
noted an improvement in general health with a longer period allowed between
blood transfusions.
7.) Barnes J., Resch K-L., Ernst E. Homoeopathy for Post-Operative Ileus: A
Meta-Analysis. Journal of Clinical Gastroenterology, 1997, Dec, 25, 4, 628-
633. Separate trials examining the effects of homoeopathic treatment for post-
operative ileus after abdominal or gynaecological surgery when compared with
placebo, specifically, for the time to first flatus after surgery. Subsequent analysis
showed that homoeopathy provided superior results to placebo.

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8.) Bell IR, Lewis DA, Brooks AJ, Schwartz GE, Lewis SE, Walsh BT, Baldwin
CM. Improved clinical status in fibromyalgia patients treated with
individualized homeopathic remedies versus placebo. Rheumatology
(Oxford). 2004 May;43(5):577-82. 53 people suffering from fibromyalgia took
part in this trial, comparing individualised homoeopathic treatment to placebo.
The levels of tender points and tender point pain as well as quality of life, mood
and general health were assessed by the practitioners and subjects involved in the
trial. 3 months after commencing treatment, all parameters were found to be
improved by the use of homoeopathy when compared to placebo.
9.) Belon P, Banerjee P, Choudhury SC, Banerjee A, Biswas SJ, et al. Can
administration of potentized homeopathic remedy, Arsenicum album, alter
antinuclear antibody (ANA) titre in people living in high-risk arsenic
contaminated areas? I. A correlation with certain hematological
parameters. Evid Based Complement Alternat Med. 2006 Mar; 3 (1):99-107. To
investigate whether or not potentised Arsenicum album has an effect on arsenic-
induced elevations of antinuclear antibody (ANA), selected inhabitants of arsenic
affected villages in India’s West Bengal were randomly assigned to receive either
Arsenicum album or placebo. After 2 months of administration, it was found that
not only did the remedy provide superior results in reducing the ANA titre, it also
caused a correction of arsenic-induced haematological changes such as total
count of red blood cells and white blood cells, packed cell volume, haemoglobin
content, erythrocyte sedimentation rate and blood sugar level.
10.) Belon P, Banerjee A, Karmakar SR, et al. Homeopathic remedy for arsenic
toxicity? Evidence-based findings from a randomized placebo-controlled
double blind human trial. Sci Total Environ. 2007 Jul 10. This was a pilot study
carried out on 25 people from an Indian village where arsenic contamination was
endemic and 18 people from another Indian village without arsenic
contamination. These people were randomly assigned to receive either
Arsenicum album 30C or a succussed placebo control. After 2 months on either
active medicine or placebo, these people had their blood and urine assessed for
arsenic as well as several widely accepted toxicity biomarkers and pathological
parameters related to arsenic toxicity. The use of Arsenicum album 30C had a
beneficial effect on these biomarkers. It was also found to improve the appetite
and general health of those people who previously exhibited signs and symptoms.
of arsenic toxicity.

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11.) Berrebi A, Parant O, Ferval F, Thene M, Ayoubi JM, Connan L, Belon P.
Treatment of Pain due to Unwanted Lactation with a Homeopathic
Preparation given in the Immediate Post-Partum Period. Gynecology,
Obstetrics and Biological Reproduction, 2001, June, 30, 4, 353-7. 71 post-
parturient women who were unwilling or unable to breast feed were divided into
2 groups, one being given a placebo and the other group being given a mixture
of Apis 9C and Bryonia 9C, to determine the effects of either on lactation pain.
A significant improvement was noted in the group using the mixture, when
compared to those in the placebo group.
12.) Bignamini M, Saruggia M, Sansonetti G. Homeopathic Treatment of Anal
Fissures using Nitricum acidum Berlin Journal on Research in Homoeopathy,
1, 4/5, 286-287, December 1991. Patients using Nitricum acidum 9C once daily
in a double blind placebo controlled trial found subjective relief with the
medicine over the placebo.
13.) Bornhoft G, Wolf U, Ammon K, et al. Effectiveness, safety and
costeffectiveness of homeopathy in general practice - summarized health
technology assessment. Forsch Komplementarmed. 2006;13 Suppl 2:19-29.
This was an effectiveness and safety study on homeopathy carried out for the
Swiss Federal Office for Public Health. Using Internet-based resources, manual
search and contact with experts, and assessed according to internal and external
validity criteria, investigators found that the trend was in favour of a therapeutic
benefit from homeopathic intervention. In addition, it was stated by the authors
of the study that, “…effectiveness of homeopathy can be supported by clinical
evidence and professional and adequate application be regarded as safe.”
14.) Brigo B, Serpelloni G, Homoeopathic Treatment of Migraine Berlin
Journal on Research in Homoeopathy, 1, 2, March, 1991, 98-106. In this
randomised, placebo controlled double blind study, 60 people suffering from
migraine were treated using constitutional homoeopathy over a period of 4
months. Those patients in the control group experienced a reduction in migraine
frequency from 9.9 attacks per month to 7.9 per month, while those in the
treatment group reduced their monthly attack rate from 10 to between 1.8 and 3
per month.
15.) Cairo J, Elliot BE, Barnouin J, Fleites P, Araoz A, Morales M, Verdura T,
Sanchez M, Serrano C, Alvarez JL, Veillard JJ. Homeopathy in Cuban
Epidemic Neuropathy: An Open Clinical Trial. British Homoeopathic
Journal, 2001, 90, 150-157. In this uncontrolled trial, 15 people suffering from

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optic endemic neuropathy (group 1) and 16 people suffering from peripheral
epidemic neuropathy (group 2) were given homeopathic Carbon sulph and
homeopathic Tabacum for 30 days. The subjects were assessed for improvement
in neurologic and ophthalmologic tests on commencement and again at 90 days
after commencement of the trial. Those in group 1 experienced an averaged
improvement of 73% and group 2 of 12.5%.
16.) Campistranous- Lavout JL., et al. Hypertension Trial. Boletin Mexicano,
1999, 32, 42- 47. 68 people suffering from mild to moderate hypertension were
enrolled in a double-blind randomised clinical trial comparing individualised
homoeopathic therapy with placebo. Successful results were obtained with 82%
of those using homoeopathy compared with 57% of those using placebo.
17.) Castellsague API, Sturza CM. Retrospective Study in Asthma, Revista
Homeopatica AMBH, 1998, 37, 5-21. In this multi-centre retrospective
(uncontrolled) analysis, 196 people were treated for asthma with homoeopathy.
of the 196, 54 were claimed to have been cured and improvement was seen in a
further 117.
18.) Cavalcanti AM, Rocha LM, Carillo R Jr, Lima LU, Lugon JR. Effects of
homeopathic treatment on pruritus of haemodialysis patients: a randomised
placebo-controlled double-blind trial. Homeopathy. 2003 Oct;92(4):177-81.
Pruritis, commonly experienced by those undergoing haemodialysis, was treated
in 20 subjects under double-blind placebo-controlled randomised trial conditions
comparing individualised homoeopathic treatment to placebo. Assessments were
made at 15, 30, 45 and 60 days treatment, and after collating the results,
researchers found that homoeopathic management reduced pruritis by 49%. The
majority of the reduction in pruritis had occurred by day 30.
19.) Chapman EH, Weintraub RJ, Milburn MA, Pirozzo TO, Woo E.
Homoeopathic Treatment of Mild Traumatic Brain Injury. Journal of Head
Trauma and Rehabilitation, 14, 6, December 1999, 521-42. In a randomised,
double blind, placebo controlled trial involving 60 subjects and a 4 month follow-
up period, homoeopathy provided significant improvement in parameters using
measures such as “Difficulty with Situations”, “Symptoms Rating Scale” and a
“Participation in Daily Activities” scale.
20.) Chapman EH. Homeopathic treatment of patients with persistent mild
traumatic brain injury. British Homeopathic Journal, 2000, 89, Suppl 1,S60.
In a randomised, placebo-controlled trial, 50 people with persistent mild

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traumatic brain injury were treated either with their constitutional homeopathic
remedy or placebo. The homeopathic treatment provided superior results to those
from the placebo control.
21.) Clark J, Percivall AA. Preliminary Investigation into the Effectiveness of
the Homoeopathic Remedy, Ruta graveolens, in the Treatment of Pain in
Plantar Fasciitis. British Journal of Podiatry, 2000, 3, 3, 81- 85. In a randomised
double-blind trial, 14 people suffering from plantar fasciitis were given Ruta
graveleons 30C or placebo. Those using the Ruta reported a greater level of pain
relief than those using placebo.
22.) Clover A, Ratsey D. Homoepathic Treatment of Hot Flushes. British
Homoeopathic Journal, 2002, 91, 75-79. Researchers at the Tunbridge Wells
Homeopathic Hospital in the UK enrolled 31 female outpatients who had
complained of menopausal flushes in this trial. They were treated using
individualised homeopathic management and after their initial consultation and
at least one follow up, patients completed their own self-assessment rating of the
treatment. 79% of the women enrolled in the study reported a reduction in both
the severity and frequency of hot flushes as a result of the treatment.
23.) Colin P. Homeopathy and respiratory allergies: a series of 147 cases.
Homeopathy. 2006 Apr;95 (2):68-72. In this case series, 147 consecutive patients
suffering from respiratory allergy who attended a private homeopathic clinic
were
assessed for their response to constitutional homeopathic treatment. Of these
patients, 105 were sufferers of ear, nose and throat allergies. Only 2 of these
patients failed to respond to treatment and none experienced an exacerbation of
symptoms. The other 42 patients were sufferers of pulmonary allergies, all except
5 of whom experienced relief, with 2 of these experiencing an exacerbation of
symptoms.
24.) Davidson JRT, Morrison RM, Shore J, Davidson RT, Bedayn G.
Homeopathic Treatment of Depression and Anxiety. Alternative Therapies, 3,
1, January 1997, 46-49. In this trial, 12 subjects suffering from major depression,
social phobia or panic disorder, were treated for 7 to 80 weeks with individually
prescribed homoeopathic remedies and assessed on a clinical global
improvement scale (CGIS) or self-rated SCL-90 scale and the Social Phobia
Scale (SPS). Subjects were given homoeopathic treatment either because they
asked for it directly or because conventional treatment had been unsuccessful.

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The overall response rates for homoeopathy were 58% on the CGIS and 50% on
the SCL-90 and SPS.
25.) Derasse M, Klein P, Weiser M. The effects of a complex homeopathic
medicine compared with acetaminophen in the symptomatic treatment of
acute febrile infections in children: an observational study. Explore (NY).
2005 Jan;1(1):33-9. In this non-randomised observational study carried out in 38
Belgian clinics, 198 children suffering from acute febrile infections were
assessed for their response to either acetaminophen or a combination of
homeopathic medicines. The children had their infection symptoms, which
included fever, cramps, disturbed sleep, crying, and difficulties eating or
drinking, assessed and graded for a response to their respective medicines. After
taking the results from all variables into account, it was found that the
homeopathic combination was as effective as acetaminophen. The tolerance to
medicines was also assessed as part of this trial and in this respect it was found
that the homeopathic combination was superior to the acetaminophen.
26.) Dorfman P, Lassere NM, Tetau M, Homoeopathic Medicines in
Pregnancy and Labor, Cahiers de Biotherapie, 94, April 1987, 77-81. In this
randomised double blind trial involving 93 women, a combination of
homeopathic Caulophyllum, Actea racemosa, Arnica, Pulsatilla and Gelsemium,
all in 5C potency, was used to determine its effect on the length of labor and
complication rates. The medicine was used from the beginning of the ninth month
of pregnancy, and reduced the average time of labor to 5.1 hours, in comparison
to the placebo, the use of which was associated with an average labor time of 8.5
hours. The rate of complications for those using the homoeopathic combination
was 11.3% while the complication rate under placebo was 40%.
27.) Eid P, Felisi E, Sideri M; Applicability of Homoeopathic Caulophyllum
thalictroides during labour. British Homoeopathic Journal, October, 1993,
82, 245-248. 22 women experiencing their first pregnancies were given
homoeopathic Caulophyllum and their post-treatment deliveries compared to 34
labours retrospectively selected on the criteria used to select the test subjects. On
analysis it was found that the women who were given the homoeopathic remedy
had a reduction of the duration of labour by an average of 90 minutes.

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28.) Ernst E, Saradeth T, Resch KL, Complementary Treatment of Varicose
Veins.. Phebology, 1990, 5, 157-163. Over a period of 24 days, the effects of a
homoeopathic complex preparation and placebo on varicose veins were tested in
a double-blind trial of 61 people suffering from this condition. The homoeopathic
complex produced an averaged 44% improvement in the condition while those
given the placebo experienced an averaged worsening of the disorder.
29.) Ferley JP, Zmirou D, D'Adhemar D, Balducci F. A Controlled Evaluation
of a Homoeopathic Preparation in the Treatment of Influenza-like
Syndrome. British Journal Clinical Pharmacology, 1989, Mar, 27, 3, 329-335.
487 people suffering from influenza were assigned to either Oscillococcinum
(Anas barb.) 200CK or placebo, twice daily for 5 days. Significant results were
achieved with the medicine over the placebo in all areas measured. This trial was
repeated in 1998 (Papp R, Schuback G, Beck E, Burkard G, Bengel J, Lehrl S,
Belon P. Oscillococcinum in Patients with Influenza-like Syndromes. British
Homeopathic Journal, April 1998, 87, pp69-76) with 372 peoplewith the same
results.
30.) Fisher P., Greenwood A, Huskisson EC, Turner P and Belon P. Effect of
Homoeopathic Treatment on Fibrositis. British Medical Journal, 5 August,
1989, 365-366. Patients using Rhus tox 6C three times daily in a double blind
placebo controlled crossover trial found significant relief with the medicine over
the placebo.
31.) Fisher P. An Experimental Double-blind Clinical Trial method in
Homoeopathy- Use of a Limited Range of Remedies to Treat Fibrositis.
British Homoeopathic Journal, 1986, July, 142-7. 24 subjects suffering from
fibrositis were treated for the condition for 3 months with Arnica, Bryonia or
Rhus tox, depending upon the similarity between the individuals’ symptoms
and the clinical picture for the remedy. Using scores for pain, number of tender
spots, and sleep quality to determine the response to the therapy, these remedies
produced a statistically significant improvement, but only when the remedy was
well indicated.
32.) Frass M, Linkesch M, Banyai S, et al. Adjunctive homeopathic treatment
in patients with severe sepsis: a randomized, double-blind, placebo-
controlled trial in an intensive care unit. Homeopathy. 2005 Apr; 94, In this
study, 70 people admitted to an intensive care unit suffering from severe sepsis
were treated either with individualised homeopathic treatment or placebo. On
reviewing the signs of sepsis, organ failures, need for mechanical ventilation and

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other parameters at 180 days after beginning treatment, 76% of the patients using
homeopathy met survival criteria versus 50% of those on placebo.
33.) Frass M, Dielacher C, Linkesch M, et al. Influence of potassium
dichromate on tracheal secretions in critically ill patients. Chest. 2005 Mar:
936-41. Stringy tracheal secretions often complicate or even prevent extubation
of people breathing with continuous positive airway pressure. This issue
provoked the development of a study involving 50 people breathing
spontaneously with continuous positive airway pressure who were randomly
assigned to receive either 5 globules twice daily of Kali bich. 30C or the same
dose and frequency of placebo globules. The study results were assessed using
the amount of tracheal secretions from day 2 of the study, the amount of time
spent by the subjects in the ICU in which they were staying and the time until
successful extubation. After the results were assessed, it was found that those
who’d been given the Kali bich. produced less tracheal secretions than those on
placebo, their stay in the ICU was shorter than those on placebo as was their time
to successful extubation.
34.)Frei H, Thurneysen A. Treatment for Hyperactive Children: Homeopathy
and Methylphenidate Compared in a Family Setting. British Homoeopathic
Journal, 2001, 114 children attending a paediatric practice where conventional
and homeopathic medicines were used, and who were previously diagnosed with
ADHD, were given individualised homoeopathic medicines (increasing
potencies of the most similar LM remedy). On a parent assessed basis (confirmed
by the clinician), if a minimum 50% improvement was not noted within a certain
period of time they were placed on Methylphenidate. 75% of the children
responded to homoeopathy and 22% required Methylphenidate. 3% of patients
did not respond to either regime.
35.) Frei H, Thurneysen A. Homeopathy in Acute Otitis Media in Children:
Treatment Effect or Spontaneous Resolution? British Homeopathic Journal,
2001, Oct, 1990. In a study involving 230 children with acute otitis media,
homoeopathic treatment was compared with placebo to determine whether
homoeopathic treatment provided a faster resolution of symptoms than placebo.
After 12 hours, 72% of those using homoeopathy experienced significant relief
of symptoms, which was 2.4 times faster than the response to placebo.
36.) Frei H, Everts R, von Ammon K, et al. Homeopathic treatment of children
with attention deficit hyperactivity disorder: a randomised, double blind,
placebo controlled crossover trial. European Journal Paediatrics. 2005 Dec,

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83 children diagnosed as suffering from ADHD using DSMIV criteria were
treated with individually prescribed homeopathic medicines. Using the Connor’s
Global Index scale it was determined that 63 of these children responded to
treatment. These children were then randomised to receive either placebo or
homeopathic medicines for 6 weeks and at this point were crossed over to receive
placebo if they’d been using the homeopathic or visa versa. At the end of this
period it was found that homeopathic therapy provided significantly better results
than placebo.
37.)Frenkel M, Hermoni D. Effects of Homeopathic Intervention on
Medication Consumption in Atopic and Allergic Disorders. Alternative
Therapies in Health and Medicine, 2002, Jan-Feb. In a study carried out at the
Technicon-Israel Institute in Haifa, Israel, 48 patients were treated for allergic
disorders with both homoeopathic and conventional medicines, and monitored
for their level of use of the conventional medicines. Over the 3 month monitoring
period, 56% of patients reduced their conventional medication use by an average
of 60%.
38.) Friese KH, Kruse S, Ludtke R, Moeller H. The Homoeopathic Treatment
of Otitis Media in Children. International Journal of Clinical Pharmacology
and Therapeutics 1997, In this trial, 131 children suffering from medically
diagnosed otitis media were split into two groups. 28 were treated by a team of
four ear, nose and throat practitioners using singly or in combination, nasal drops,
antibiotics, secretolytics or antipyretics (Group B). 103 children were treated by
one homoeopath using single homoeopathic remedies (Group A). The average
duration of pain for Group A was 2 days, as opposed to 3 days for Group B.
70.7% of the Group A children were free of recurrences within the first year of
treatment and 29% had a maximum of 3 recurrences while in Group B, 56.5%
were free of recurrences within the first year of treatment and 43.5% had a
maximum of 6 recurrences.
39.) Friese KH, Zabalotnyi DI. Homeopathy in acute rhinosinusitis : A double-
blind, placebo controlled study shows the efficiency and tolerability of a
homeopathic combination remedy. HNO (Organ of the Deutsche Gesellschaft
der Hals-, Nasen- und Ohrenärzte) 2006 December, Using a randomized,
doubleblind study method, 144 people with acute rhinosinusitis were treated with
a either a combination of homeopathic remedies (Group A) or placebo (Group B)
and assessed at days 0, 7, 14 and 21 of treatment using a 5 point sinusitis symptom
score (the worst score being 20). After analysing the results it was found that
those in Group A experienced a drop in symptom scores from 12.1+/-1.6 to 5.9+/-

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2.0 points after 7 days. Those in Group B found a decrease from 11.7+/-1.6 to
11.0+/-2.9 points (p<0.0001). The final results showed that the homeopathic
combination resulted in freedom from complaints in 90.3% of the patients and
improvement in a further 8.3%, whereas in the placebo group, the complaints
remained unchanged or became worse in 88.9% of the patients.
40.) Gasssinger CA, Wunstel G, Netter PA Controlled Clinical Trial for
Testing the Efficacy of the Homoeopathic Drug, Eupatorium perfoliatum,
D2 in the
Treatment of Common Cold. Arznei Forsch, 1981, 732-736. Patients were
randomly assigned to receive either Aspirin or Eupatorium perfoliatum 2X. The
latter was found to be as effective as Aspirin in reducing the duration and severity
of symptoms.
41.) Gerhard I, Wallis E. Individualised Homeopathic Therapy for Male
Infertility, Homeopathy, 2002, 133-144. An observational pilot study
investigated the effect of individualised homeopathic therapy for 45 sub-fertile
males, with specific reference to sperm count and quality, hormone levels and the
general level of health. Sperm count and sperm motility were improved by
homeopathy and the improvement was comparable with conventional treatment.
42.) Gibson RG, Gibson SL, Mac-Neill AD, Gray GH, Dick WC, Buchanan WW.
Salicylates and Homoeopathy in Rheumatoid Arthritis. British Journal of
Clinical Pharmacology, 1978, 391-395. In this study, carried out at the Glasgow
Homeopathic Hospital, 41 people suffering from rheumatoid arthritis were
treated with enteric coated aspirin and 54 people suffering from the same
condition were treated with individualised homeopathic treatment. The results of
the two forms of therapy were compared at the end of the trial and it was found
that those on homeopathic treatment did considerably better than those on aspirin.
In addition, 16 of the 41 people taking aspirin during the trial experienced side
effects while those taking homeopathic experienced no side effects.
43.) Gibson RG, Gibson SL. Homoeopathic Therapy in Rheumatoid
Arthritis: Evaluation by Double Blind Clinical Therapeutic Trial. British
Journal Clinical Pharmacology 1980, 453-459. 46 patients using a number of
different homoeopathic medicines, prescribed according to homoeopathic
principles, were given this medicine or a placebo with their normal anti-arthritic
drug. The trial was carried out blind and significant results were achieved with
the homeopathic medicine over the placebo in all areas measured.

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44.) Gimeno L.Q. Homoeopathic Treatment of Human Papilloma Virus
infections previously treated by Other Methods. British Homoeopathic
Journal, October 1996, 194-197. In this study, 14 people suffering from recurrent
HPV, previously unresponsive to microsurgical procedures, were treated with
individualised homeopathy and assessed via cytology prior to treatment, during,
and 1 year after commencing treatment. At the final 1year assessment, 11 of the
14 subjects were declared to be cured.
45.) Gmnunder R, Kissling R. The Efficacy of homeopathy in the treatment of
chronic low back pain compared to standardized physiotherapy. Zeitschrift
für Orthopädie und ihre Grenzgebiete, 2002 Sep-Oct;503-8. In this controlled,
randomised, prospective study, 43 people suffering from chronic low back pain
were treated for two months either by homeopathy or by standardised
physiotherapy. Assessment based on the initial and final clinical investigations,
an Oswestry questionnaire, and visual analogue scale, found that the most
successful method of treatment was homeopathy.
46.) Goldstein MS, Glik D. Use of and satisfaction with homeopathy in a
patient population. Altern. Ther. Health Med. 1998 March:60-5. Carried out in
9 homeopathic clinics in the Los Angeles area, this study was done to determine
the success or otherwise of constitutional homeopathic practice as assessed by
the people who’d undergone this therapy. The study also looked at the
characteristics of the people involved in the study. Information was provided by
77 clients. At 4 months after treatment, 71% of clients reported improvement in
their health status. This is contrasted with the fact that 80% of all clients enrolled
in this survey had had previous orthodox medical treatment for their condition
which they had found unsuccessful. The most common presenting complaints
involved the respiratory, gastrointestinal and female reproductive systems and
most clients were highly educated but had little knowledge of homeopathy prior
to their treatment with it.
47.) Guthlin C., Lange O., Walach H. Measuring the Effects of Acupuncture
and Homeopathy in General Practice: An Uncontrolled Prospective
Documentation Approach. Biomedical Central Public Health, 2004. 5000
people were treated for various ailments using acupuncture, and 900 people were
treated using individualised homeopathy, by medical practitioners in a number of
clinics throughout Germany. Most of these people had previously been treated
using conventional drugs. After treatment, of those being treated using
acupuncture, 36% stated that they felt “very much better” and 49% felt,

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“somewhat better”. Of those being treated using homeopathy, 39% stated that
they felt “very much better” and 38% felt, “somewhat better”.
48.) Haidvogl M, Riley DS, Heger M. Homeopathic and conventional
treatment for acute respiratory and ear complaints: a comparative study on
outcome in the primary care setting. BMC Complementary Alternative
Medicine 2007 March; The aim of the authors of this study was to compare the
effectiveness of homeopathic treatment for acute respiratory and ear complaints
with orthodox medical treatment for the same conditions. 1577 clients from 57
clinics from Austria, Germany, The Netherlands, Russia, Spain, Ukraine, the
United Kingdom and the USA were enrolled in the study. They were asked to
rate their response to either therapy at 14 days after beginning treatment. 86.9%
of those given homeopathic medicines declared that they had had either a
complete recovery or major improvement in their symptoms. 86% of those given
orthodox medical treatment reported the same thing. Subgroup analysis found
that 88.5% of children given homeopathic reported a complete recovery or major
improvement in symptoms whereas 84.5% of those given orthodox medical
treatment reported similar success. In addition, the onset of improvement within
the first 7 days after treatment was significantly faster in those with homeopathic
treatment, both in children and adults.
49.) Haila S, Koskinen A, Tenovuo J. Effects of homeopathic treatment on
salivary flow rate and subjective symptoms in patients with oral dryness: a
randomized trial. Homoeopathy. 2005 July, 94, 175-81. In this blind, placebo-
controlled study, 28 people diagnosed with xerostomia (dryness of the mouth)
were randomly assigned to receive either placebo or individually prescribed
homeopathic medicines. Assessed using un-stimulated and wax-stimulated
salivary flow rates and visual analogue scales at the end of the trial, 26 of those
people using homeopathic treatment and none using placebo were found to have
had significant relief. Following the assessment of these results those on placebo
were switched to homeopathic therapy, after which all experienced relief from
their xerostomia.
50.) Harrison RE, Burge TS, et al. Homoeopathic Treatment of Burn Scars.
British Homoeopathic Journal, October 1993, 82, 252-254. 4 people suffering
from hypertrophic scarring subsequent to burns were treated with homeopathic
Graphites for 3 months. All 4 subjects were relieved of these symptoms. No
controls were used for comparison.

15
51.) Hill N, Stam C, Tuinder S, van Haselen RA. A Placebo Controlled Clinical
Trial investigating the efficacy of a Homoeopathic After-Bite Gel for
Reducing Mosquito bite induced Erythema. European Journal
Pharmacology, 1995, 103-108. 68 people were bitten at least 3 times by
mosquitoes. One of the bites was treated with an afterbite gel containing
homoeopathic ingredients, another of the bites was treated with a placebo gel,
and the third bite remained untreated. Erythema associated with the bites was
measured before and regularly after treatment at all of the bite sites and the
subjects rated the degree of pruritis experienced at the sites. The active gel
provided results that were significantly superior to the placebo or no treatment.
52.) Hitzenberger G, Kom A, Dorsci M, Bauer P, Wohlzogen FX. Controlled
randomised Double Blind study for the Comparison of the Treatment of
Patients with Essential Hypertension with Homoeopathic and
Pharmacologically Effective Drugs. Weiner Klinische Wochenschrift
(Klinische Wochenschrift), 1982, 665-670. In this randomized double-blind
cross-over trial, 10 people suffering from essential hypertension were treated
either with standard pharmaceutical products or homeopathic medicines.
Pharmaceuticals were found to provide superior blood pressure reducing effects
but homeopathic were found to be the better choice for the management of the
subjective symptoms of hypertension.
53.) Issing W., Klein P., Weiser M. The homeopathic preparation Vertigoheel
versus Ginkgo biloba in the treatment of vertigo in an elderly population: a
double-blinded, randomized, controlled clinical trial. Journal of Alternative
and Complementary Medicine. 2005, Feb. 155-60. Over a 6 week period, 170
people with an age range of 60- 80 years with atherosclerosis related vertigo were
treated for this condition using either a homeopathic combination or herbal
gingko biloba. Using a patient-assessed dizzyness questionnaire and practitioner
assessment via line walking and other tests as methods of measurement,
participants found that the homeopathic combination provided outcomes as good
as those with gingko.
54.) Itamura R, Hosoya R. Homeopathic Treatment of Japanese patients with
intractable Atopic Dermatitis. Homeopathy, 2003, 108-114. In this
uncontrolled study, 17 people suffering from intractable atopic dermatitis
undertook individualised homoeopathic treatment for the condition in
conjunction with their existing pharmaceutical therapy, for a period of up to 2
years and 7 months. On an objective assessment and the patient’s own

16
assessment, all patients experienced in excess of 50% improvement by the end of
the trial.
55.) Itamura R. Effect of homeopathic treatment of 60 Japanese patients with
chronic skin disease. Complement Therapeutic Medicine. 2007 June; 115-20. 60
people were enrolled in this uncontrolled trial which was carried out in Obitsu
Sankei Hospital in Kawagoe which was designed to determine the effect of
individualised homeopathic medicines on several common skin disorders. These
disorders included atopic dermatitis, eczema, acne, urticaria, psoriasis and
alopecia universalis. Treatment occurred over a period of 3 months to 2 years and
7 months and subjects were permitted to use conventional dermatological
treatments while taking part in the trial. Using the trial participants’ own
assessment, improvement or otherwise was assessed using a nine-point scale
similar to the Glasgow Homeopathic Hospital Outcome Scale. On this basis, 6
people reported a complete recovery, 23 reported a 75% improvement, 24 found
a 50% improvement and 7 had a 25% improvement). In all, 88.3% of patients
reported over 50% improvement.
56.) Jacobs J, Jiminez J, Gloyd SG, et al. Treatment of Acute Childhood
Diarrhoea with Homoeopathic Medicine. Paediatrics, May, 1994, 719-725. In
a randomised, placebo controlled trial with 81 children suffering from acute
diarrhoea, individually prescribed homoeopathic medicines were found to be
superior to placebo.
57.) Jacobs J, Jimenez M, Malthouse S, Chapman E, Crothers D, Masuk M, Jonas
WB. Acute Childhood Diarrhoea- A Replication. Journal of Alternative and
Complementary Medicine, 6, 2000, 131-139. In a replication of a previous trial
carried out by Jacobs and others, 116 Nepalese children aged 6 months to 5 years
suffering from diarrhoea were given an individualised homoeopathic medicine or
placebo over a 5 day period. Results assessed at the end of this period showed
homeopathy to be superior to placebo as a means of relieving diarrhoea.
58.) Jacobs J, Springer DA et al. Homeopathic treatment of acute otitis media
in children: a preliminary randomized placebo-controlled trial. Paediatrics
Infection Disease Journal, 2001, 177-83. 75 children suffering from acute otitis
media were given homeopathic treatment or were given treatment with placebo.
On assessment it was found that homeopathy provided an improved outcome
from this condition.

17
59.)Jacobs J, Jonas WB, Jimenez-Perez M, Crothers D. Homeopathy for
childhood diarrhea: combined results and meta-analysis from three
randomized, controlled clinical trials. Paediatrics Infection Disease Journal.
2003 Mar; 229-34. In this metaanalysis (an analysis carried out to determine
overall trends in a group of similar studies) three double blind clinical trials of
diarrhoea in 242 children aged 6 months to 5 years were analysed as one group.
The children received either an individualised homeopathic medicine or a
placebo, for 5 days after each unformed stool. Records were kept by parents and
the duration of diarrhoea was defined as the time until there were less than 3
unformed stools per day for 2 consecutive days. Diarrhoea ceased in those taking
homeopathic medicines after 3.3 days and after 4.1 days in those using placebo.
60.)Jacobs J, Herman P, Heron K, Olsen S, Vaughters L. Homeopathy for
menopausal symptoms in breast cancer survivors: a preliminary
randomized controlled trial. Journal of Alternative and Complementary
Medicine. 2005, Feb, 21-7. This study compared the effects of an individualised
homeopathic prescription with a homeopathic combination and placebo in 55
women suffering from menopausal symptoms for a period of 1 year. Both the
individualised and combination homeopathic therapy provided an improvement
in symptoms over placebo, with the individualised homeopathy showing the best
outcomes over the first 3 months of the assessment period.
61.) Jeffrey SL, Belcher HJ. Use of Arnica to Relieve Pain after Carpal Tunnel
Release Surgery. Alternative Therapies in Health and Medicine, 2002, Mar-Apr,
66-8. 37 patients who had undergone carpal tunnel release surgery were given a
combination of Arnica tablets and Arnica ointment or placebo. After 2 weeks of
therapy, the group using Arnica reported a significant reduction in pain.
62.) Karow JH, Abt HP, Fröhling M, Ackermann H. Efficacy of Arnica
montana D4 for Healing of Wounds after Hallux valgus Surgery compared
to Diclofenac. Journal of Alternative Complementary Medicine 2008 Jan-
Feb;14(1):17-25. In this randomised, doubleblinded, parallel group study, 88
people who were recovering from foot surgery were randomly assigned to receive
either Arnica 4X at a rate of 10 pilules 3 times daily or Diclofenac 50mg 3 times
daily. Both therapies were used for 4 days following the surgery. At day 4,
subjects were assessed for their postoperative irritation, mobility, pain level, and
their use of analgesics. Analysis of the results at this point showed that Arnica
and Diclofenac provided the same level of reduction in wound irritation
(including swelling) and mobility. Subjective assessment by patients rated Arnica
as superior to Diclofenac for mobility. Diclofenac was superior to Arnica for pain

18
reduction and there was no significant difference in analgesic use during the 4
days following surgery. It was also noted in the study that Arnica was 60%
cheaper than Diclofenac.
63.) Kassab S, Cummings M, Berkovitz S, van Haselen R, Fisher P.
Homeopathic Medicines for Adverse effects of Cancer Treatments. Cochrane
Database Systematic Review. 2009 April; Cochrane Reviews investigate the
effects of interventions for prevention, or treatment of illness, or rehabilitation
from illness, in a healthcare setting. Most Cochrane Reviews are based on
overviews of randomized controlled trials and other forms of evidence that are
deemed to be appropriate. This review was conducted to determine what, if any,
evidence (in the opinion of the Cochrane reviewers) exists for the treatment by
homeopathy of the effects of conventional cancer therapies. A search through
numerous databases revealed 8 controlled trials involved in this area of study, 7
of which were placebo controlled and 1 of which was against an active treatment.
In total, the trials covered the outcomes of 664 people who’d been variously
suffering from the adverse effects of radiotherapy, chemotherapy or breast cancer
treatment. Of the 8, 2 trials exhibited beneficial effects from homeopathy. One of
these involved a comparison between the effects of a topical corticosteroid and a
homeopathic mother tincture of calendula for the prevention of dermatitis from
radiotherapy where the calendula proved to be superior to the drug. The other
involved the successful use of a homeopathic complex for stomatatitis caused by
chemotherapy.
64.) Kayne S. A Pilot Trial to Study the Perceived Effectiveness of
Homoeopathic remedies bought Over The Counter (OTC) in British
Pharmacies. Journal of the Royal London Homoeopathic Hospital NHS Trust,
1997, January 23-24, 1000 questionnaires were sent to 8 UK pharmacies,
requesting them to pass the questionnaires to customers. These, questionnaires
asked the customers whether or not they found OTC homoeopathic medicines
effective for the conditions for which they were purchased. A total of 257 users
responded, and the accumulated results showed that 83% of respondents felt
better after taking the product.
65.) Keil T, Witt CM, Roll S, Vancea W, Webera K, Wegscheiderb K, Willich SN.
Homoeopathic versus Conventional Treatment of Children with Eczema: A
comparative Cohort Study. Complementary Therapies in Medicine (2008) 15-
21. This was a prospective, multi-centre, parallel-group, comparative cohort
study was conducted in urban and mixed urban—rural regions of Germany. 118
children suffering from clinically defined eczema seen at 54 homeopathic

19
practices and 64 conventional medical practices were treated for the condition
with the respective therapeutic protocols normally used in these clinics, i.e.
individualised homeopathic or conventional medical therapy. Treatment
occurred over a period of 12 months and the outcomes of the 2 different methods
of therapy were assessed at 6 months and 12 months by the children or their
parents on the basis of eczema signs and symptoms and the quality of life.
Overall, on the basis of clinical symptoms and quality of life, there was little
difference in the response rates of both groups to their respective therapies
although at 12 months after starting treatment, those children who were treated
homeopathically had a greater level of recovery from symptoms than those
treated with conventional medicine. No adverse reactions were reported for either
group.
66.) Kim LS, Riedlinger JE, Baldwin CM, Hilli L, Khalsa SV, Messer SA, Waters
RF. Treatment of seasonal allergic rhinitis using homeopathic preparation
of common allergens in the Southwest Region of the US: A randomized,
controlled clinical trial. Annals of Pharmacotherapy. 2005, April, 617-24. In
this double-blind trial, 34 people diagnosed with moderate to severe seasonal
allergic rhinitis were randomly assigned to receive either placebo or a
combination of potentised allergens (made from the pollens of trees, grasses or
weeds identified as allergens). After the 4 week treatment period using 2 sprays
3 times a day of either the potentised allergen mix or placebo, the trial subjects
were assessed on the basis of their allergy specific symptoms using 3 separate
questionnaire formats (RQLQ, MOS SF-36 and the WPAI). The potentised
allergen mix showed significant positive changes compared to placebo.
67.) Klopp R, Niemer W, Weiser M. Microcirculatory effects of a homeopathic
preparation in patients with mild vertigo: an intravital microscopic study.
Microvasc. Res. 2005, 69.The aim of this non-randomized, open study was to test
the effectiveness of a homeopathic combination product on variables related to
microcirculation in 16 people suffering from vestibular vertigo, compared to a
control group of 16 untreated people also suffering from vestibular vertigo.
Measurements were carried out in two areas (defined by selecting 60 blood-cell
perfused nodal points of arterioles, venules, and capillaries with a mean diameter
> or = 40 microns): the cuticulum/subcuticulum of the inside left lower arm and
an area 5 mm behind the left earlobe. After 12 weeks of treatment, those people
receiving the homeopathic preparation exhibited an increased number of nodal
points, increased flow rates of erythrocytes in both arterioles and venules,
increased vasomotion, and a slight reduction in hematocrit vs. baseline. None of
these changes were observed in the control group. Measurements were also made

20
of partial oxygen pressure and the numbers of cell-wall adhering leucocytes, both
of which were significantly increased in the test group compared to the control
group. All of these parameters were associated with a reduction in the severity of
the vertigo symptoms, both on patient as well as practitioner assessment.
68.) Kneusel O, Weber M, Suter A. Arnica montana Gel in Osteoarthritis of
the Knee: an open, multi-center clinical trial. Advanced Therapies, 2002, Sep-
Oct, 209-18. In this uncontrolled study, 79 people suffering from mild to
moderate osteoarthritis of the knee were given a gel containing Arnica and asked
to apply it twice daily. They were assessed at 3 and 6 weeks for pain, stiffness
and functional ability of the knee. Both assessments showed a significant
reduction in pain and stiffness, and a significant improvement in the functional
ability of the knee.
69.) Kulkarni A, Nagarkar BM, Burde GS. Radiation protection by use of
homoeopathic medicines. Proceedings from the 8th Conference of Radiation
Oncologists of India, Bombay, December 1986, reported in Hahnemann
Homoeopath Sand, 1988 Jan,12, 20-23. 82 patients receiving radiotherapy were
randomly assigned to receive placebo, Cobaltum 30C or Causticum 30C as a
means of assessing the effects of these against dermatological reactions to the
radiotherapy. The homeopathic medicines provided a significant reduction in the
degree of radiation reactions when compared to placebo.
70.) Lamont J., Homoeopathic Treatment of Attention Deficit Hyperactivity
Disorder (ADHD). British Homoeopathic Journal, 1997, 196-200. 43 children
with ADHD were given either a placebo or an individualised homeopathic
medicine, in accordance with a double blind partial crossover dose regime. When
the results were compared at the end of the trial, it was found that the
homeopathic treatment for ADHD was superior to that using placebo.
71.) Launso L, Kimby CK, Henningsen I, Fonnebo V. An exploratory
retrospective study of people suffering from hypersensitivity illnesses who
attend medical or classical homeopathic treatment. Homeopathy. 2006
April:73-80. This study reports the results of orthodox medical treatment
compared to the homeopathic treatment of various hypersensitivity illnesses in
88 people. 34 of these people were treated using orthodox medical means and 54
using constitutional homeopathy. 24% of those treated medically experienced an
improvement in their condition while 57% of those treated with homeopathy
experienced similar relief.

21
72.) Ludke R, Weisenauer M. A Meta-analysis of Homeopathic Treatment of
Pollinosis with Galphimia glauca. Wiener Medizinische Wochenschrift, 1997,
323-327. In this analysis, 7 randomised double-blind placebo controlled trials and
4 trials without placebo controls were examined to determine the therapeutic
benefits of Galphimia glauca in pollinosis. In all studies except for one,
Galphimia showed significant benefit over placebo where placebo controls were
used, or showedsignificant clinical benefit where the remedy was not compared
to placebo. The recovery rates for Galphimia were comparable with those seen
with conventional anti-histamines, but without the same side effects.
73.) Maas HPJA. Ulcerative Colitis treated with Homoeopathy British
Homoeopathic Journal, July 1993, 179-185. In this retrospective case analysis,
24 people suffering from ulcerative colitis were treated in an Argentinian clinic
using constitutional homoeopathy over periods of up to 19 years. Of these 24, 16
patients were assessed as having good outcomes.
74.) Manchanda RK, Mehan N, Bahl R, Atey R. Double Blind Placebo
Controlled Clinical Trials of Homoeopathic Medicines in Warts and
Molluscum contagiosum, CCRH Quarterly Bulletin, 1997, 25-29. This trial was
reported in two parts, one to evaluate the efficacy of homoeopathy for warts
(remedies included Ruta graveolens, Nitricum acidum, Dulcamara, Causticum
and Thuja) the other to evaluate the homoeopathic remedy, Calcarea carbonica,
for Molluscum contagiosum. Placebo controlled studies involving a total of 147
subjects using single remedies in 30C potencies three times daily, 200C twice
daily and 1M daily, for 15 days, showed that homoeopathy was superior to
placebo. Thuja was the most successful of the remedies used for warts.
75.) Marian F, Joost K, Saini KD, von Ammon K, Thurneysen A, Busato A.
Patient Satisfaction and Side Effects in Primary Care: An observational
study comparing Homeopathy and Conventional Medicine. BMC
Complementary Alternative Medicine 2008 Sep. 52: This was a study carried out
by the Swiss Federal Office of Public Health designed to determine levels of
patient satisfaction and the perception of side effects following the use of
homeopathic medicine. It was part of a national program designed to evaluate
complementary and alternative medicine use in Switzerland. The bulk of the data
used in the study came from questionnaires filled in over a specific 4 day period
supplied by physicians using conventional medicine, physicians using
homeopathic medicine, and from patients who’d filled in questionnaires mailed
to them 1 month after treatment. 170 practitioners were involved in the study. A
total of 3126 questionnaires were received by the researchers and analysis of

22
these revealed the following. 21% of those treated with homeopathy reported
“complete resolution” of the presenting complaint versus 28% of those on
conventional therapy and 53% reported “complete satisfaction” with
homeopathic treatment versus 40% of those given conventional therapy. The rate
of side effects reported by those using homeopathy was less than those given
conventional medicine.
76.) Maronna U, Weiser M, Klein P. Comparison of the Efficacy and
Tolerance of Zeel comp. and Diclofenac for the Oral Treatment of
Gonarthrosis. Biological Medicine, 2000, 29, 3, 157-158. Diclofenac, a non-
steroidal inflammatory drug, is a commonly prescribed medicine for rheumatic
diseases. The effects of this drug were compared to those of Zeel, a homoeopathic
complex preparation, with 121 people suffering from gonarthrosis. The trial was
designed as a randomised, double-blind, actively controlled parallel study.
Assessments for pain, stiffness and functional ability were carried out at 2, 4, 6
and 10 weeks after commencing treatments and by the end of the 10 week period,
there were no statistical differences observed in the outcomes of both treatment
regimes. The homoeopathic complex product and the drug were equally effective
in the management of gonarthrosis.
77.) Mathie RT, Farrer S. Outcomes from homeopathic prescribing in dental
practice: a prospective, research-targeted, pilot study. Homeopathy. 2007
April;74-81; This paper presented the results of a study into the effectiveness of
individualised homeopathic medicines for the management of common dental
complaints and the effectiveness of a specific protocol used to collect such data.
14 dentists who routinely practice homeopathy contributed data to the study and
data from the observations of and by 726 individual patients were collected. Of
the 496 patients who were able to be followed up, 90.1% reported a positive
outcome, 1.8% experienced a deterioration of the condition and 7.9% of patients
reported no change.
78.) Matusiewicz R. The effect of a homoepathic preparation on the clinical
condition of patients with corticosteroid dependant bronchial asthma.
Biomedical Therapy, 1997, June, 70-74; In this double-blind, randomised,
placebo-controlled study, 40 people suffering from corticosteroid- dependant
bronchial asthma were given either placebo or a combination homeopathic
formula, every 5 to 7 days by subcutaneous injection. Using standard spirometry
and granulocyte function to measure the response, researchers found that the
combination product provided superior results to placebo.

23
79.) McCutcheon LE. Treatment of anxiety with a homoeopathic remedy
Journal of Applied Nutrition, 1996, 2-6: 72 people with above-average levels of
anxiety were enrolled in this double-blind, placebo-controlled trial and assigned
to either a test or control (placebo) group to assess the relative benefits of a
combination homeopathic product designed to relieve anxiety. Using sleep loss
as a measure of anxiety, the combination product produced results that were
better than those from placebo.
80.) Milewska G, Trzebiatowska-Trzeciak O. Homoeopathic Treatment of
Alcohol Withdrawal British Homoeopathic Journal, October 1993, 249-251:
Alcohol withdrawal and delirium tremens experienced by 30 alcoholics was the
focus of this uncontrolled study carried out in a Polish medical clinic. Patients
were treated with individualised homeopathy and their progress followed for 2
months. The treatment resulted in a reduced duration of alcohol withdrawal time
and delirium tremens in all patients.
81.) Mohan GR, et al, Cervical Spondylosis- a Clinical Study, British
Homoeopathic Journal, July 1996, 131-133; In this uncontrolled study, 154
people suffering from cervical spondylosis were prescribed either homoeopathic
Calcium fluoride, or a remedy selected via repertorisation of their mental and
physical general symptoms, and their progress monitored for 1 year. Of those
given Calc fluor, clinical improvement was seen in 60% of cases. 48% of those
given the remedy arrived at by repertorisation reported clinical improvement.
82.) Mohan GR, Anandhi KS. Efficacy of homeopathic drugs in dermatitis of
atopic diathesis. Homoeopathic Links, 2003, Winter, 257-260. The authors
treated 31 people suffering from either atopic skin and respiratory symptoms, or
atopic skin symptoms alone. Both groups were treated with individualised
homeopathic therapy over a period of 5 years. During a 6 month assessment
period following this treatment, the authors determined that 41% of the group
with skin and respiratory symptoms achieved not less than a 76% improvement
in symptoms and 58% of the group with skin symptoms alone achieved this
outcome.
83.) Mohan GR. Efficacy of Homeopathy in Childhood Asthmas.
Homeopathic Links, Summer 2007, Vol 20, 104-107. This paper reports of work
done in India by homeopath, GR Mohan, looking at the results of the
homeopathic treatment of 81 children suffering from clinically defined asthma
who had previously been treated unsuccessfully with conventional medicine.
This open study involved the use of individually prescribed homeopathic

24
medicines for a period of 2 years as a means of reducing the recurrence of asthma
attacks. Results were assessed according the 12 point Modified Borg Scale, a
subjective scale used to assess the severity of dyspnoea. At the end of the allotted
2 year period, the results were analysed and it was found that asthma had become
controlled in 60.5% of children who’d been treated with homeopathy, and some
control was achieved in a further 21%. 12.3% of the group failed to respond to
the treatment. The medicines used most frequently in this study were Arsenicum
album, Merc solubilis, Hepar sulph, Arsenicum iod, Antimony tart, Pulsatilla and
Calc carb.
84.) Mojaver YN, Mosavi F, Mazaherinezhad A, Shahrdar A, Manshaee K..
Individualized homeopathic treatment of trigeminal neuralgia: an
observational study. Homeopathy. 2007 April: 82-6: This uncontrolled study,
carried out in the Department of Oral Medicine at Iran’s Rafsanjan University of
Medical Sciences, was designed to discover if individually prescribed
homeopathic medicines could provide relief from medically diagnosed
trigeminal neuralgia. 15 people suffering from the condition were enrolled in the
study and after receiving their individual prescriptions they were assessed
monthly using a Visual Analogue Scale to gauge the severity of their symptoms.
After the results were assessed at 4 months it was found that individualised
homeopathic treatment was associated with an average reduction in pain intensity
of more than 60%.
85.) Müller-Krampe B, Oberbaum M, Dipl-Math PK, Weiser M. Effects of
Spascupreel versus hyoscine butylbromide for gastrointestinal cramps in
children. Pediatrics Int. 2007 June:328-34: In this observational cohort study,
204 children under 12 years of age suffering from gastrointestinal spasms and
cramps were given either hyoscine butylbromide, a drug commonly prescribed
for these conditions, or Spascupreel, a homeopathic complex. After a 1 week
period of treatment, the results from these interventions were assessed by a
practitioner reviewing reports from the child’s parent or carer using severity of
spasms, pain or cramps, sleep disturbances, eating or drinking difficulties, and
the frequency of crying, to measure outcomes according to a 4 point scale.
Analysis of the results showed that both medicines provided similar levels of
benefit.
86.) Muscari-Tomaioli G, Allegri F, Miali E, Pomposelli R, Tubia P, Targhetta
A, Castellini M, Bellavite P. Observational Study of Quality of Life in patients
with Headache, receiving Homeopathic Treatment. British Homoeopathic
Journal, 2001,189-197: In this study, 53 people suffering from headaches were

25
treated by the individual study authors using constitutionally prescribed
homeopathic medicines, completing SF-36 health-related quality of life
questionnaires before and 4-6 months after beginning the treatment. More the
60% of the subjects experienced an improvement in the condition.
87.) Oberbaum M, Schreiber R, Rosenthal C, Itzchaki M. Homeopathic
Treatment in Emergency Medicine, a case series. Homeopathy, 2003,44-47;
In this study, 15 people suffering from orthopaedic trauma were treated in a
medical centre with homoeopathy, in addition to standard medical treatment.
Treatment was commenced 24 hours after admission. All patients initially
received homeopathic Arnica 200C and anxiety was treated with Aconite,
Opium, Ignatia or Arsenicum album, all in 200C potency. 24 hours following this
treatment, the majority of patients reported a reduction in pain and anxiety. 48
hours after admission, patients were treated with individualised homoeopathic
remedies. At discharge, 67% of patients rated the homoeopathic treatment as
successful.
88.) Oberbaum M, Galoyan N, Lerner-Geva L, et al. The effect of the
homeopathic remedies Arnica montana and Bellis perennis on mild
postpartum bleeding—a randomized, double-blind, placebo-controlled
study: preliminary results. Complement Therapeutic Medicine 2005 Jun,87-90;
Forty women experiencing postpartum bleeding were randomly assigned to
receive a mixture of Arnica 30C and Bellis 30C, Arnica 6C and Bellis 6C, or
placebo. Mean haemoglobin values were measured at 72 hours post-partum, at
which point it was found that those women given homeopathic therapy
experienced significantly less change in haemoglobin values than those given
placebo.
89.) Pai PN; Thiosinaminum in the Treatment of Plantar Fasciitis with
Calcaneal Spurs. British Homoeopathic Journal, October, 1992, 173-175; In
this uncontrolled study, 43 people suffering from plantar fasciitis and calcaneal
spurs were treated with homeopathic Thiosinimum, Thiosinimum and Merc cor,
or Thiosinimum and Merc biniod. Thiosinimum alone proved to be the therapy
most likely to be helpful in resolving recently developed cases.
90.) Pai PN. Nephrotic Syndrome. British Homoeopathic Journal, 1969; In a
case series, 23 children suffering from clinically diagnosed nephrotic syndrome
were treated using individualised homeopathic medicines for periods varying
from 1 month to 7 years. Subjects received acute and/or chronic treatment for the
condition and in several acute episodes, corticosteroid therapy was used, in

26
addition to homeopathic management. For the majority of the children treated
either with homeopathic or a combination of homeopathic and corticosteroid
therapy, the severity of the symptoms they had previously experienced was
reduced. The main homeopathic remedies used in the cases mentioned in this
study included homeopathic Apis mellifica, Arsenicum album, Natrum
muriaticum and Silica.
91.) Pomposelli R, Piasere V, Andreoni C, Costini G, Tonini E, Spalluzzi A,
Observational study of Homeopathic and Conventional therapies in patients
with Diabetic Polyneuropathy. Homeopathy. 2009 Jan.:17-25; Researchers at
the University of Verona in Italy designed this observational study to compare
the effects of homeopathic therapy with conventional drug therapy for diabetic
neuropathy. Over a 12 month period, 32 patients treated with homeopathy and 29
patients given conventional drug therapy were assessed for clinical symptoms
and quality of life at baseline, 6 months and 12 months after beginning treatment.
Improvement from baseline polyneuropathy symptoms was noted in both groups
but only those treated homeopathically reached outcomes that were statistically
significant. Both groups experienced improvements in blood pressure and body
weight as well as levels of fasting blood glucose and glycated haemoglobin. In
addition, only those in the homeopathy group noted an improvement in quality
of life scores over the period of the study. It was also noted that homeopathic
treatment was more economical than the conventional drug alternative.
92.) Popov A.V. Homoeopathy in the Treatment of Patients with
Fibromyoma of the Uterus. British Homoeopathic Journal, October 1992, 164-
167; In this study, 84 women suffering from various forms of uterine fibromyoma
were prescribed individualised homeopathic medicines over a period of 1 to 3
years. Assessments at the end of the treatment period found that pain was
improved in 79% of the subjects, abnormal bleeding was improved in 75% of
subjects and in the majority of subjects the treatment resulted in a reduction of
fibromyoma volume.
93.) Rabe A., Weiser M., Klein P. Effectiveness and tolerability of a
homoeopathic remedy compared with conventional therapy for mild viral
infections. International Journal of Clinical Practice, 2004, Sept. 827-32: In this
observational cohort study, 485 people with symptoms of mild viral infection
(fever, headache, myalgia, cough or sore throat), were treated either via

27
conventional medical means or with a homeopathic combination product. On a
practitioner evaluation basis, at the end of the treatment period, the homeopathic
combination provided a successful outcome in 78% of cases and conventional
treatment in 52% of cases.
94.) Rai Y. Treatment of Drug Dependants with Homoeopathy. CCRH
Quarterly Bulletin,1994, 25-28: 261 people suffering from symptoms related to
the withdrawal from drugs of dependence were treated with individualised
homoeopathy. Remedies were given at 8 to 12 hours after ceasing use of the drug.
209 (80%) of the subjects found the treatment to be effective.
95.) Rastogi DP, Singh VP, Singh V, Dey SK, Rao K. Homeopathy in HIV
infection. British Homoeopathic Journal, 1999, 49-57; In a randomised, double-
blind placebo controlled trial, 50 people with asymptomatic HIV infection and
50 people with symptomatic (persistent generalised lymphadenopathy) HIV
infection and were given either placebo or an individualised homoeopathic
medicine. Using numbers of pre and post treatment CD4+ve T-lymphocytes as a
measure, it was found that homoeopathic treatment was successful for
symptomatic HIV sufferers, but not for asymptomatic sufferers.
96.) Reilly R, Taylor MA, McSharry C, et al. Is Homoeopathy a Placebo
Response? Lancet, Oct 18, 1986, 881- 885:144 people suffering from hayfever
were enrolled in a randomised, placebo controlled trial. The use of 30C mixed
grass pollens provided better clinical outcomes than placebo.
97.) Riley D, Fischer M, Singh B, Haidvogl M, Heger M. Homeopathy and
Conventional Medicine: An Outcomes Study Comparing Effectiveness in a
Primary Care Setting. Journal of Alternative and Complementary Medicine,
2001, April, 149-59: In this study, carried out by 30 investigators, at 6 clinics in
4 countries, 456 patients suffering from upper respiratory allergies, lower
respiratory allergies or ear disorders were assigned to one of two groups- those
prescribed homeopathic medicines (group A) or those prescribed standard
medical treatment (Group B). The outcome measure was the response to
treatment after 14 days, as well as the speed of recovery, rate of side effects, level
of general satisfaction and length of consultation. The response to treatment
within 14 days was 82.6% in Group A and 68% in Group B. For recovery speed,
67% of Group A recovered within 3 days and 57% of Group A recovered at this
speed. The side effect rate for Group A was 8% compared to 22% for Group B.
Those claiming to be very satisfied with their respective treatments were 79% of

28
Group A and 65% of Group B. The majority (60%) of both groups received
consultations that lasted for between 5 and 15 minutes.
98.) Riveron-Garrote M, et al. Clinical Trial of Asthma, Boletin Mexicano,
1998; 54-61; In this double-blind, randomised, placebo-controlled trial, 63
asthma sufferers were treated for 4 months with either specific homoeopathic
remedies or placebo. Assessed using peak flow rates, 97% of those taking
homoeopathic medicines and 12% or those taking placebo experienced an
improvement.
99.) Robertson A, Suryanarayanan R, Banerjee A Homeopathic Arnica
montana for post-tonsillectomy analgesia: a randomised placebo control
trial. Homeopathy. 2007 January,17-21; In this trial, 190 people undergoing
tonsillectomy were randomly assigned to receive Arnica 30C or a placebo at a
dose rate of 2 tablets 6 times in the first post-operative day and then 2 tablets
twice a day for the next 7 days. On a patient-assessed 14 days post-operative
visual analogue scale for pain, those given the Arnica 30C were found to have a
statistically significant decrease in pain scores compared to placebo.
100.) Robinson T. Responses to homeopathic treatment in National Health
Service general practice. Homeopathy. 2006 Jan.:9-14: This study was designed
to determine the level of effectiveness of homeopathy as used in a general
practice clinic where the standard 10 minute consultation time applies. To do this,
5,331 patient files, taken from one 12 month period in one general practice clinic,
were examined and those files that described a consultation where a homeopathic
medicine was given were separated out for analysis. This produced a total of 489
consultations that resulted in a homeopathic medicine prescription. Of these, 78%
of patients had a positive response to their treatment with homeopathy, 19% had
no response, and 3% had a negative response.
101.) Sanchez-Resendiz J, Guzman-Gomez F. Polycystic Ovary Syndrome.
Boletin Mexicano de Homeopatica, 1997, 11-15; 36 women suffering from
Polycystic Ovary Syndrome (PCOS), and fitting the mental picture of the
homoeopathic remedy Pulsatilla, were given Pulsatilla 6C, 4 hourly throughout
the day for 2 weeks after the end of menstruation, and this was repeated for 4
consecutive cycles. At the end of the trial 30 of the 36 women had complete
disappearance of the symptoms of PCOS and the production of normal ovulating
follicles and a further 4 of the 36 became asymptomatic.

29
102.) Saruggia M, Corghi E. Effects of homoeopathic dilutions of China rubra
on intradialytic symptomatology in patients treated with haemodialysis.
British Homoeopathic Journal, 1992, April, 86-88: Using a double-blind,
randomised, crossover, placebo- controlled trial design, 35 people with end-stage
renal failure on regular haemodialysis were assessed to determine their response
to either placebo or China rubra 9C. Those people using the China experienced
statistically significant relief from asthenia, headache and lethargy.
103.) Schlappack O. Homeopathic treatment of radiation induced itching in
breast cancer patients. A prospective observational study. Homeopathy,
2004, 210-215; 25 women suffering from post-radiotherapy induced itching were
treated at the University of Vienna’s Department of Radiotherapy and
Radiobiology using individualised homeopathic medicines. After assessment (1-
27 days after beginning the treatment) it was found that homeopathic treatment
had been successful in 21 of the women enrolled in the study.
104.) Schmidt CA. Double Blind, Placebo-Controlled Trial: Arnica montana
Applied Topically to Subcutaneous Mechanical Injuries. Journal of the
American Institute of Homeopathy, Winter 1996, 186-193; In this trial 141
runners were asked to use topical preparations containing placebo, Arnica 1X or
Arnica 6C, and to rate the effectiveness of the preparations at relieving post-
exercise muscle soreness. The preparation containing Arnica provided superior
results to placebo and preparation containing Arnica 1X was reported to be
superior to that containing Arnica 6C.
105.) Schmiedel V, Klein P. A complex homeopathic preparation for the
symptomatic treatment of upper respiratory infections associated with the
common cold: An observational study. Explore (NY). 2006 Mar;2 (2):109-14:
379 people suffering from upper respiratory infections were given either
conventional medical treatment (antihistamines, anti-tussives, or nonsteroidal
anti-inflammatory drugs) or a combination homeopathic product. Using variables
such as fatigue, sensation of illness, chill/tremor, aching joints, overall severity
of illness, sum of all clinical variables, and temperature to assess the effects of
either form of therapy, the researchers found that both approaches were effective,
although the homeopathic combination provided faster relief from symptoms
(77% were improved within 3 days compared to 62%).
106.) Schneider C, Klein P, Stolt P, Oberbaum M. A homeopathic ointment
preparation compared with 1% diclofenac gel for acute symptomatic

30
treatment of tendinopathy. Explore (NY). 2005 Nov. 446-52: In this non-
randomised, observational study carried out in 95 German homeopathic and
conventional medical clinics, 357 people with various forms of tendinopathy
were given either an ointment containing a mixture of homeopathic remedies, or
Diclofenac (a popular nonsteroidal anti-inflammatory agent), for up to 28 days.
Using a four-degree scale on pain-related variables related to motility, and on
overall treatment outcome, the ointment containing the mixture of homeopathic
remedies provided a therapeutic outcome that was superior to Diclofenac.
107.) Schneider C, Schneider B, Hanisch J, van Haselen R. The role of a
homoeopathic preparation compared with conventional therapy in the
treatment of injuries: an observational cohort study. Complementary Therapy
Medicine 2008 Feb.:22-7: The researchers in this study set out to compare the
effectiveness of a homeopathic combination product (Traumeel) with
conventional medical treatment ,for injuries. 125 people suffering from various
musculoskeletal injuries were treated either with the homeopathic combination
or conventional medicine and were assessed for resolution of the complaint at the
end of the trial period. At this point, the 59.4% of the group receiving the
homeopathic combination had complete resolution compared with 57.8% of the
group treated with conventional medicine. 6.3% of the latter group experienced
adverse reactions to the treatment and none of those on the homeopathic
combination experienced side effects.
108.) Schroder D, Weiser M, Klein P. Efficacy of a Homeopathic Crataegus
preparation compared with usual therapy for Mild Cardiac Insufficiency:
Results of an Observational Cohort Study. European Journal of Heart
Failure,
2003, June, 319-26: In a non-randomised cohort study, 212 people suffering from
mild cardiac insufficiency were given Cralonin, a homoeopathic combination
product, or a combination of an ACE inhibitor and diuretic (a combination
medical therapy normally prescribed for this condition). Both products were
similarly effective in controlling the condition.
109.) Seeley BM, Denton AB, Ahn MS, et al. Effect of homeopathic Arnica
montana on bruising in face-lifts: results of a randomized, double-blind,
placebo-controlled clinical trial. Arch. Facial Plast. Surg. 2006 Jan-Feb. 54-9:
In this trial, 29 people who were undergoing facelifts were randomised to receive
either perioperative homeopathic arnica, or placebo. They were examined
postoperatively for bruising at days 1, 5, 7 and 10. Assessment done at days 1
and 7 showed a signification reduction in bruising when compared to placebo.

31
110.) Sevar R. Audit of outcome in 829 consecutive patients treated with
homeopathic medicines. British Homeopathic Journal, 2000,178-187: In this
study, consecutive patient files in a single homeopathic clinic were examined to
determine the success or otherwise of this form of treatment. Of the 829 patients
surveyed, 61% had a sustained improvement from their constitutional
homeopathic treatment.
111.) Sevar R. Audit of outcome in 455 consecutive patients treated with
homeopathic medicines. Homeopathy. 2005 Oct., 215-21; This study examined
the effect of individualised homeopathic treatment of 455 consecutive patients in
a homeopathic medical clinic who’d previously had unsuccessful orthodox
medical treatment or were considered to be unsuitable for orthodox medical
treatment. Of these, 67% derived benefit from homeopathic therapy, and 33%
were able to stop or maintain a substantial reduction in their pharmaceutical drug
therapy.
112.) Shackleton M.F., Tondora CM, Whiting S, Whitney M. The Effect of
Homeopathic Coca on High Altitude Mountain Sickness. Complementary
Health Practice Review, 2000, 45- 55: 11 members of the 1998 Everest Challenge
Expedition were given either placebo or Coca 200C daily. Assessed on the
primary symptoms of altitude sickness as well as oxygen saturation, those using
the homoeopathic medicine showed significantly less signs and symptoms of
altitude sickness.
113.) Shealy CN, Thomlinson PR, Cox RH, Bormeyer V. Osteoarthritis Pain:
A Comparison of Homoeopathy and Acetaminophen. American Journal of
Pain Management, July 1998, 89-91: In this trial, 65 sufferers of osteoarthritis
(OA) were split into 2 groups, and through a double blinding process were given
either a homoeopathic medicine or Acetaminophen, a commonly prescribed drug
for pain relief in OA. Researchers found that homoeopathy provided a level of
pain relief that was superior to Acetaminophen, and produced no adverse
reactions.
114.) Smith SA, Baker AE, Williams JH. Effective Treatment of Seborrhaic
Dermatitis using a Low Dose Oral Homeopathic Medication. Alternative
Medicine Reviews, 2002, Feb., 59-67: 41 patients with seborrhaic dermatitis
received either placebo or a homoeopathic combination product for 10 weeks.
Significant improvement was seen in the test group when compared to those
using placebo.

32
115.) Spence DS, Thompson EA, Barron SJ. Homeopathic treatment for
chronic disease: a 6-year, university-hospital outpatient observational study.
Journal of Alternative and Complementary Medicine 2005 Oct., 793-8: This
study looked at the effectiveness of individualised homeopathic therapy over a 6
year period in a UK homeopathic hospital outpatient department. The results
from 6544 consecutive patients were examined, and when compared to baseline
observations it was found that of these patients, 70% reported an improvement in
their conditions.
116.) Stanton HE. Test and Anxiety- A Five Drop Solution. Education News,
1981,12-15: In this trial, 40 students suffering from test-induced anxiety were
given either homeopathic Argentum nitricum 12X or placebo. The level of test-
induced anxiety was significantly reduced from the homeopathic medicine when
compared to the placebo and this effect appeared to persist over time.
117.) Steinsbekk A, Ludtke R. Patients' assessments of the effectiveness of
homeopathic care in Norway: a prospective observational multicentre
outcome study. Homeopathy, 2005, 10-16; In this prospective uncontrolled
observational multi-centre outcome study, 654 people who’d visited 80
Norwegian homeopaths were asked to assess, via a Visual Analogue Scale (VAS)
the effectiveness of this form of treatment comparing the VAS score at their first
consultation with the VAS score 6 months later. After the results were collated it
was found that 70% of those people visiting a Norwegian homeopath reported a
meaningful improvement in their main complaint 6 months after the initial
consultation.
118.) Strauss LC. The Efficacy of a Homeopathic Preparation in the
Management of Attention Deficit Hyperactivity Disorder. Biomedical
Therapy, 2000, 197- 201: 20 children suffering from ADHD, were given either
placebo or a homoeopathic combination (Heel Selenium-Homaccord) and were
assessed in accordance with pre and post test conduct and psychosomatic
problems, impulsivity and anxiety. The homoeopathic combination provided
superior results to those of placebo.
119.) Taylor MA, Reilly D, Llewellan-Jones RH, McSharry C, Aitchison TC.
Randomised Controlled Trial of Homoeopathy versus Placebo in Perennial
Allergic Rhinitis with Overview of Four Trial Series. British Medical Journal,
2000,471-476: 19 August. 51 people suffering from allergic rhinitis were

33
randomly assigned either homeopathically potentised allergens or placebo. Those
given the medicine experienced significant relief over those assigned the placebo.
120.) Trichard M, Chaufferin G, Nicoloyannis N. Pharmaco-economic
comparison between homeopathic and antibiotic treatment strategies in
recurrent acute rhinopharyngitis in children. Homeopathy. 2005, 3-9. In this
6 month prospective study involving 499 children suffering from acute
rhinopharyngitis, the effectiveness, quality of life and cost of treatment with
homeopathic (Group A) versus antibiotic (Group B) medicines, as prescribed by
French medical practitioners, were assessed. Effectiveness, as measured by the
numbers of episodes occurring subsequent to treatment, was 2.71 for Group A
and 3.97 for Group B and quality of life as measured by the ParEnt-Qol scale was
21 for Group A versus 30 for Group B, which indicates a higher quality of life
for those in Group A. In regard to costs, average direct medical costs were 88
Euros for Group A and 99 for Group B. Parental sick-leave affected 9.5% of the
parents from Group A and 30% for Group B.
121.) Tuten C, McLung J. Reducing Muscle Soreness with Arnica Montana.
Alternative and Complementary Therapies, December 1999, 369- 372: 23 people
were given either placebo or Arnica 6X for the management of delayed onset
muscle soreness after exercise. Outcomes were assessed subjectively by the
participants themselves, and by creatinine kinase (CK) assays. CK levels are
indicative of muscle or connective tissue damage. While there was only a small
subjective difference between the 2 groups, the people using Arnica 6X produced
less CK than those using placebo, which tends to indicate that those using Arnica
experienced less tissue damage on exertion.
122.) Tveiten D, Bruset S, Borchgrevink CFS, Norsch J. Arnica and Muscle
Soreness. Focus on Alternative and Complementary Medicine (FACT), 1998,
155-156: 46 competitors in the 3 day 1995 Oslo marathon were randomly
assigned either homeopathic Arnica or placebo twice daily and assessed for
muscle soreness after the event. Those using Arnica found significant relief with
the medicine over the placebo.
123.) Tveiten D, Bruset S. Effect of Arnica D30 in marathon runners. Pooled
results from two double-blind placebo controlled studies. Homeopathy. 2003
Oct. 187-9: In this study combing the effects of two clinical trials on homeopathic
Arnica D30 (30X), the homoeopathic remedy was compared to placebo in 82
Oslo marathon runners for muscle enzymes, electrolytes and creatinine
(indicating cell damage) and the subjective control of muscular soreness. Those

34
runners taking Arnica experienced less muscle soreness when compared to
placebo, but there was no difference between both groups for muscle enzymes,
electrolytes and creatinine.
124.) Van Erp VM, Brands M. Homoeopathic Treatment of Malaria in Ghana.
British Homoeopathic Journal, 1996, April, 66-70: In a randomised double blind
trial with limited numbers of subjects, homoeopathic treatment was compared to
treatment by Chloroquine. The group using homoeopathic medicines experienced
an 83.3% improvement, while the group using Chloroquine experienced a 72%
improvement within the same time period.
125.) Van Haselen RA, Fisher PA. A randomized controlled trial comparing
topical piroxicam gel with a homeopathic gel in osteoarthritis of the knee.
Rheumatology, 2000, July. 714-9: In this controlled double-blind trial, 172
people with radiographically confirmed symptomatic osteoarthritis of the knee
were randomly assigned to receive treatment with either piroxicam gel (a
commonly prescribed non-steroidal anti-inflammatory gel) or a gel containing 3
homeopathic ingredients (Symphytum, Rhus tox and Ledum). At the conclusion
of the trial it was found that the gel containing the homeopathic ingredients was
at least as effective as the piroxicam gel.
126.) Van Wasserhoven M., Ives G. An Observational Study of Patients
receiving Homeopathic Treatment. Homeopathy, 2004,3-11: 782 people
suffering from a wide range of diseases who had visited 80 general medical
practices in Belgium were treated with individualised homeopathic medicines
over an average period of 9 years and 2 months. Most of these people had
previously been treated using conventional drugs. The outcomes from this
treatment were assessed both by the patients and the practitioners via
questionnaires. 13% of the patients assessed in the study expressed satisfaction
with previous conventional treatment and 89% of patients expressed satisfaction
with their homeopathic treatment.
127.) Von Gasssinger C. A., Wunstel G., Netter P. A Controlled Clinical Trial
for Testing the Efficacy of the Homoeopathic Drug Eupatorium perfoliatum
D2 in the Treatment of Common Cold. Arzneimittel Forschung, 1981,732-736:
In this trial, 53 people suffering from the common cold were given either
acetylsalicylic acid or Eupatorium perfoliatum 2X. Eupatorium was shown to be
as effective as the acetylsalicylic acid in its ability to provide benefit to those
suffering from the common cold.

35
128.) Walach H, Möllinger H, Sherr J, Schneider R. Homeopathic Pathogenetic
Trials produce More Specific than Non-Specific Symptoms: Results from
Two Double-Blind Placebo Controlled Trials. Journal Psychopharmacol.
2008 July: 543-52: Professor Harold Walach of the University of Northampton
and his colleagues have made something of a habit of carrying out provings of
homeopathic medicines (particularly Belladonna) within fairly rigidly controlled
settings. In this instance the researchers set up 2 studies, both of which were
carried out in blinded conditions. The first of these compared the symptoms seen
in a controlled proving of homeopathically prepared Ozone with the effects of a
placebo used in the same way. The second test compared the symptoms seen in
a controlled proving of homeopathically prepared Ozone and Iridium, used
individually, with the symptoms seen from the use of placebo. On analysis, the
results showed that both Ozone and Iridium, when used under proving conditions,
produced a statistically significant level of symptoms specific to the original
provings for the homeopathic preparation.
129.) Waldschütz R, Klein P. The homeopathic preparation Neurexan Vs.
Valerian for the Treatment of Insomnia: An observational study. Scientific
World Journal. 2008 April: 411-20: This German study, conducted across 89
clinics, compared the effects of a homeopathic combination preparation to
valerian on sleep latency (the time take to fall asleep), sleep duration, the quality
of sleep, and daytime fatigue, over a period of 28 days. 409 people were enrolled
in the study and analysis of the results found an improvement from both
medicines with a reduction in latency time (37.3 minutes for the combination
versus 38.2 minutes for valerian) and increase in sleep duration (2.2 hours for the
combination versus 2 hours for valerian). The primary difference between the 2
interventions appeared to be that the homeopathic combination resulted in less
daytime fatigue than valerian- 49% versus 32%.
130.) Weatherley-Jones E, Nicholl JP, Thomas KJ, Parry GJ, McKendrick MW,
Green ST, Stanley PJ, Lynch SP. A randomised, controlled, triple-blind trial
of the efficacy of homeopathic treatment for chronic fatigue syndrome.
Journal of Psychosomatic Research. 2004, Feb. 189-97: In this well-controlled
trial, where the practitioners, trial subjects and data analysts were all blinded to
the group assignments until the end of the data collection period, individualised
homeopathic prescriptions were compared to placebo in 79 people suffering from
chronic fatigue syndrome (as determined by the Oxford criteria for CFS). The
trial was carried out over a 6 month period with monthly observations used to
determine clinical progress according to the Multidimensional Fatigue Inventory
(MFI) as a primary measure and the Fatigue Impact Scale and Functional

36
Limitations Profile as secondary measures. On the primary MFI measure, those
using the individualised homeopathy had significant improvement over placebo.
131.) Weiser M, Clasen BPE. Controlled Double Blind study of a
Homoeopathic Sinusitis Medication. Biological Therapy, 1995, 4-11: In a
randomised double-blind placebo controlled trial, 155 people suffering from
sinusitis were given either a placebo or a homoeopathic combination (Heel
Euphorbium compositum). Subjective responses showed a greater improvement
in those using the homoeopathic combination than those given placebo.
132.) Weisser M, Strosser W, Klein P. Homeopathic vs Conventional
Treatment of Vertigo. Arch Otolaryngol Head Neck Surg. 1998, Aug. 879-885:
A study group of 119 people suffering from vertigo were treated either with
betahistine hydrochloride (acting as an active control, commonly prescribed by
medical authorities for this condition) or a homoeopathic complex. Both of the
interventions were equally successful in relieving vertigo.
133.) Weiser M, Gegenheimer LH, Klein P. A Randomised Equivalence Trial
Comparing the Efficacy and Safety of Luffa comp.-Heel Nasal Spray with
Cromolyn Sodium Spray in the Treatment of Seasonal Allergic Rhinitis.
Forschende Komplementarmedizin, 1999, 6, 142-148: In this trial, 146 people
suffering from hay fever were treated with either Luffa comp.-Heel Nasal Spray
(a homoeopathic combination product) or with Cromolyn Sodium Spray (a
pharmaceutical drug commonly prescribed for hay fever). The treatment
outcomes were measured according to a quality of life scale and both medicines
provided the same level of remission of the condition, which was rapid and
persistent.
134.) Widrig R, Suter A, Saller R, Melzer J. Choosing between NSAID and
arnica for topical treatment of hand osteoarthritis in a randomised, double-
blind study. Rheumatol Int. 2007 Apr;27(6):585-91: Using a double-blind
protocol, 204 people suffering from radiologically confirmed and
symptomatically active osteoarthritis were randomly assigned to receive either
topical arnica or topical ibuprofen to be applied to the area where the condition
was active. The success or failure of the treatments was assessed according to
functional ability of the affected part and pain intensity in this area after 21 days
of continuous treatment. Assessment of the results at the end of this period found
that topical arnica was as successful as topical ibuprofen for the management of
osteoarthritis.

37
135.) Wiesenauer M, Haussler S, Gaus W. Pollinosis therapy with Galphimia
glauca. Fortschritte der Medezin, 1983, 811-814: Using a randomised, placebo-
controlled, double-blind, multi-centre design in this trial, 86 people suffering
from hay fever were treated for 5 and a half weeks with either homeopathic
Galphimia glauca 4X or placebo. Therapeutic success was seen in 83% of those
using the Galphimia and 47% of those using placebo.
136.) Wiesenauer M, Gaus W, Haussler S. Treatment of Pollinosis with
Galphimia glauca. Allergologie, 1990, 10, 359-363: 54 practitioners treated 201
people suffering from hay fever either with placebo or homeopathic Galphimia
glauca. Assessment at the end of the 5 week treatment period found that nasal
symptoms were cured or significantly improved in 77% of subjects using
Galphimia versus 46% of those using placebo and eye symptoms were cured or
significantly improved in 77% of subjects using Galphimia versus 51% of those
using placebo.
137.) Wiesenauer M, Gaus W. Proof of the Effectiveness of a Homeopathic
Preparation in Chronic Polyarthritis. Erzten Akt Rheumatol, 1991, 16, 1-9: In
this randomised, double-blind clinical trial, 111 people being treated by 6 general
practitioners for rheumatoid arthritis were given either placebo or a combination
of homeopathic Berberis, Bryonia, Ledum, Nux vomica and Ledum. Using pain,
stiffness, inflammatory signs, fatigue and a functional index to determine clinical
outcomes, at the end of the 12 week treatment period it was found that the
homeopathic combination provided superior results to those of placebo.
138.) Witt CM, Ludtke R, Baur R, Willich SN. Homeopathic medical practice:
longterm results of a cohort study with 3981 patients. BMC Public Health.
2005 Nov, 3, 5, 115: In this study, 3981 patients being treated in private
homeopathic medical clinics in Germany and Switzerland were assessed for the
effectiveness of their homeopathic treatment over a 2 year period. When
compared to baseline assessments taken immediately before treatment had
begun, the adults in the study experienced a reduction in disease severity of 52%
and children by 64%.
139.) Witt C, Keil T, Selim D, Roll S, Vance W, Wegscheider K, Willich SN.
Outcome and costs of homoeopathic and conventional treatment strategies:
a comparative cohort study in patients with chronic disorders.
Complementary Therapeutic Med. 2005 Jun;13(2):79-86: This cohort study,
carried out in Germany, examined the outcomes of homeopathic treatment
compared to the orthodox medical treatment of 493 people suffering from a range

38
of chronic illnesses including headache, lower back pain, insomnia, depression,
bronchial asthma, atopic dermatitis and allergic rhinitis. The patients’
assessments, taken at 6 months and 12 months from the beginning of the
treatment, found that homeopathy provided a greater level of improvement in
their illnesses than orthodox medical intervention. This difference appeared to be
more pronounced in children than in adults. In regard to the cost of each type of
therapy, this study showed these costs to be similar to each other.
140.) Witt CM, Ludtke R, Mengler N, Willich SN. How healthy are
Chronically Ill Patients after Eight years of Homeopathic Treatment? -
Results from a long term observational study. BMC Public Health 2008,
8:413: German academic and researcher Professor Claudia Witt has been
responsible for a number of excellent papers on homeopathy and in this, she and
co-workers drew data from 103 Swiss and German homeopathic medicine clinics
in an effort to determine the level of change to the health status of patients over
periods of 2 and 8 years, as a result of homeopathic intervention, over these times.
Data was collected from 3709 patients who were asked to assess the level of
change to the severity of their medical complaints and quality of life, at the time
of first consultation, at 2 years, and at 8 years from that point. The data from
adults and children were assessed separately and the former experienced an
average reduction in disease severity from 6.2 at baseline to 2.9 at 2 years to 2.2
at 8 years. For children, a reduction from a baseline disease severity of 6.1 to 2.1
at 2 years was noted and then to 1.7 at 8 years. Physical and mental quality of life
scores for both groups increased significantly over the study period and
interestingly, researchers found that, within the confines of this study, the
younger the patient and the more severe the medical condition, the better the
potential for the therapeutic success of homeopathy.
141.) Wolf M, Tamaschke C, Mayer W, Heger M. Efficacy of Arnica in
varicose vein surgery: results of a randomized, double-blind, placebo-
controlled pilot study. Forsch Komplementarmed Klass Naturheilkd. 2003
Oct;10(5):242-7: In this trial homeopathic Arnica D12 (12X) was compared to
placebo, to determine its effect on the size and pain of bruising after surgery.
Arnica was used once prior to surgery and then 3 times a day for 2 weeks after
surgery. 60 people participated in the trial and on completion it was found that
Arnica reduced the size of the bruising by 76% compared to 72% for placebo and
pain was reduced by 43% from arnica and by 28% from the placebo.
142.) Yakir M, Kreitler S, et al. Homoeopathic Treatment of Premenstrual
Syndrome. British Homoeopathic Journal, July, 1995, 84, 164-184: In a double

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