A Medieval Recipe Could Kill Hospital Superbugs. No, Really.

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Staph infections are one of the most pervasive and annoying bacterial infections faced by hospitals every year. It infects half a million people in the US every year, with symptoms ranging from skin infections to heart problems — and worse, some strains (commonly known as MRSA) have evolved to resist common antibiotics.

As it turns out, medieval communities also faced staph — in particular, with staph causing eye sores called styes. Our ancestors had an old-timey cure, too, written in Old English in Bald's Leechbook:

Take cropleek and garlic, of both equal quantities, pound them well together, take wine and bullocks’ gall, of both equal quantities, mix with the leek, put this then into a brazen vessel, let it stand nine days in the brass vessel, wring out through a cloth and clear it well, put it into a horn, and about night time apply it with a feather to the eye; the best leechdom.

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Christina Lee, the Viking studies professor who came across the recipe, decided to take it to a microbiologist at her university to test. They painstakingly followed the recipe — not easy, when since modern crop varieties differ significantly to the older ones.

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They tested the homebrew potion on scraps of skin taken from mice infected with methicillin-resistant Staphylococcus aureus, the most difficult-to-kill version of staph. Surprisingly, the recipe killed 90 per cent of the bacteria — the same success rate as Vancomycin, the drug hospitals use to treat MRSA. An American researcher contributing to the project found a similar rate when he repeated the effect.

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Now, researchers need to work out which particular compound worked the magic. The team also tested the individual ingredients on their own, and found no effect on the MRSA strain; it seems that there's something about steeping in a brazen vessel that bacteria just doesn't like. (Of course, it's worth mentioning that test-tube results don't always play out so well in the real world.)

The findings are due to be presented at a conference this week in Birmingham, UK. Until then, just make sure you stock up on garlic, bile salt, and wine. Particularly the wine. [New Scientist]

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