47 Startups That Launched At Y Combinator Winter 2015 Demo Day 2

Y Combinator got so big, it had to split its Demo Day in two. During today’s second wave we saw a variety of promising biotech, marketplace, enterprise, and financial tech startups. Yesterday we chronicled 50 consumer, B2B, developer, and hardware companies.

With bigger and bigger batches, the on-stage pitches are getting more bombastic as YC’s startups compete for attention. Yet this batch seemed like one of the strongest in years. After some batches around 2013 that included startups that felt more like niche features, YC is now backing big dreams for the future of medicine, money, and even marijuana.

Standard Cyborg

Standard Cyborg’s co-founder demos his company while wearing one of its 3D-Printed prosthetic legs.

 

Here’s a quick look at all 50 of the startups that presented on the record. Click through the linked descriptions to read TechCrunch’s full writeups on the companies.

Campus JobHelps college students find part-time jobs and internships. Students fill out a profile, see jobs they’re qualified for, and can quickly apply. 1300 companies are already paying Campus Job to connect them to its 100,000 students across 2200 colleges.

SeedAn online bank for small businesses. Seed uses your data to pre-qualify you for loans rather than make you hunt for them. It has a revenue share in place with a banking partner that handles the traditional stuff. It recently released its banking API and will launch its software client soon.

NextTravelZenefits for travel. 75% of corporate travel is still inefficiently booked by humans because companies want control over spending and policies. NextTravel eliminates this with a self-serve front-end for employees to book travel, and a backend open to managers who can track spending and prevent abuse.

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TheMidGame – Helping brands advertise through social media influencers. TheMidGame works with brands to find them social media stars that are relevant to their customers. Influencers connect all their social accounts to a dashboard, receive source materials from which to create content, post stories that naturally pimp the brand, and are measured by the sales they generate. TheMidGame pays the influencers and keeps a cut.

eBrandValue – Real-Time Nielsen Ratings For Brands. eBrandValue measures success of brand marketing and can predict sales by analyzing social signals from customers on Facebook, Twitter, Instagram, and other channels. For example, it was able to track liquor brand Diageo’s sales with 70% accuracy a month before the company got those sales figures by looking at what people were saying about its beverages.

Standard Cyborg3D-Printed Prosthetics. Medical prosthetics like false legs are expensive since they’re hand-made. Standard Cyborg’s founder paid $23,000 for his prosthetic leg and it can’t go in water. But Standard Cyborg can 3D print water-proof prosthetic legs that are sold for just $800. Next, it wants to build a much wider range of prosethetics.

Standard Cyborg's waterproof prosthetic leg

Standard Cyborg’s waterproof prosthetic leg

Rescue ForensicsDigitally Combatting The Child Sex Trade. Law enforcement doesn’t have the expertise or technology to track online listings of child sex slaves. Rescue Forensics helps index these criminal listings to aid authorities with tracking victims so they can be rescued, and gathering evidence for presecuting crooks. Its customers already include the FBI, Department Of Homeland Security, DOJ, and LAPD. Next, the startup wants to fight drug trafficking and terrorism recruitment.

LumiPut Your Logo On Anything. Lumi’s website lets you drag-and-drop your logo onto any type of product, from t-shirts and consumer products, to vehicles and walls. With 70% margins, it’s already profitable, and the startup cites how predecessors in branded merchandise like Zazzle and Teespring were underestimated at first. Everyone is starting their own business, and everyone needs help getting their brand out their.

Lumi helps you brand anything

Lumi helps you brand anything

Underground Cellar –  Buy On-Demand Wine And Get Free Upgrades. Wine makers don’t want to offer discounts because it teaches buyers they’re worth less. Underground Cellar helps them boost sales by offering free upgrades like bigger bottles, rarer vintages, or autographed packaging. This hooks conumers, leading Underground Cellar to have already racked up $1.2 million in revenue. Eventually, it wants to dig into other luxury verticals.

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TranscripticAWS For Biology. Founder Max Hodak hopes to enable anyone with a laptop to run a drug lab usingis a cloud-based biotech lab that tests experimental drugs using automated robots. There are nearly 30 employees now, doubling in the last year. It pulled in over $100,000 in sales 2014, allowing the company to raise $8.5 million in Series A funding and move into a new space in January.
AtomwiseSoftware For Drug Discovery. Atomwise predicts potential drug cures with the use of supercomputers, artificial intelligence and a specialized algorithm that runs through millions of molecular structures, potentially reducing the cost and time involved in making new drug discoveries. Most drug research takes months or years and millions of dollars. Atomwise utilizes AI and machine learning to enable research that costs thousands of dollars and takes just days.
Four months ago it launched a search to find existing medicines to fight Ebola. Two of the drugs predicted by Atomwise could potentially be used to cure Ebola. According to the startup they cost less than $1000 and 1 week to find.
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Spark Gift -Stock Gift Giving. People have been gifting U.S. savings bonds for years. However, savings bonds rates are now low and regulation makes them difficult to give. Spark Gift employs a technology called fractional shares. People can give a fraction of Google stock, for instance, for $20. It hopes to create new investors through education and familiarization with the stock market. 
Gradberry – Curating Technical Talent. It’s hard for an HR manager without technical knowledge to find the right software engineer for the job. Gradberry is a software engineer recommendation platform that helps the hiring manager asses engineering skills. Engineers sign up and create a profile on the platform with links to their Github projects. Employers looking for a particular skill set can scour the platform for the specific engineering skills they need. What sets them apart from other resume platforms is it uses a machine learning system that searches the web for experienced engineers and grades their code quality so that HR reps can have a better understanding of how good the code is. Gradberry already has 65 companies using the platform and is at a 45% interview growth rate. It estimates an annual revenue of $1.6 million.
Industrial Microbes –  Make Chemicals Using Natural Gas. Non-fuel chemicals such as sugar are often used as the raw material to convert chemicals, but the cost is high. Industrial Microbes uses the much cheaper natural gas to convert substances. By lowering the cost, it could be used to make biodegradable plastics and other materials.
Techlist – AngelList For Asia. Unlike Silicon Valley, Asia is fragmented and traditional press isn’t doing a good job of covering the tech startups in Asia. Techlist connects startups to investors [Disclosure: Techlist is a potential competitor to TechCrunch and CrunchBase]. The Techlist blog attracts nearly 2 million readers with a $3 million run rate. All startups are covered in English so investors can read about them on a global level. According to Techlist, there are over 800 investors that visit the site.
MeadowMedical Cannabis Delivery. In simple terms, you push a button and get marijuana. Meadow is experiencing 20% weekly growth with a 56% monthly retention rate. Like many of the on-demand medical marijuana delivery apps available, Meadow does not own or touch the marijuana. It builds the software for delivery, point of sale, and inventory management for dispensaries. This is a $2.7 billion market. It is poised to grow to over $11 billion by 2019. “Who knew marijuana would be so profitable,” co-founder David Hua told the packed YC Demo Day audience.
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ReSchedule – Rescheduling for residency programs. Rescheduling is one of the largest logistics pain points in hospitals and residency programs. Reschedule provides an end-to-end work flow to manage graduate medical education scheduling. Hospital staff usually takes hours to work schedules around. The team has developed an algorithm that can make a schedule in seconds.
Diassess – Rapid DNA test. is creating rapid, disposable DNA testing. In less than 20 minutes, for under $10 and in 3 simple steps you can find out the results for STD’s, the flu or HIV from urine or saliva. The device comes with a bar code that can be scanned into an app on a smartphone for the results of the test. Results are then delivered instantly. The process was tested recently at  the Children’s Hospital of Oakland and achieved 100% accuracy. Organizations like DARPA have supported Diasses. It is real-time detection and diagnoses in the palm of your hand. 
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Razorpay Stripe for India. Right now businesses in India need to go through a lot of paperwork to take payments. Regulation also makes it very complicated. The payments system lags behind the U.S. by 20 years. Razorpay helps businesses by providing a standardized payments gateway into this $54 billion market. It is on track to becoming the largest online payments market and Razorpay is the only startup doing anything to on-board merchants in the country. Razorpay purports to have 400 merchants using the service currently.
Direct MatchNASDAQ For Bonds. Banks make $100 billion every year for bond trading, but the transaction is made through an intermediary that takes a cut. Unlike the stock market, the bond market doesn’t have a centralized system where traders can plainly see the fees involved in the trade. Direct Match eliminates the middle man. There are already 25 institutions using the technology.
BuildScienceSmart Building Software. Nest helps regulate homes in the same way that BuildScience regulates heating and lighting for office buildings using a real-time software platform. The target market is building managers and owners of office buildings. BuildScience charges by the square foot and already manages 1 million square feet of office space with a plan to double that by summer. It is already tracking 6,000 data points with a savings of $500,000 per year.
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ShiftLabsLow-Cost Medical Devices. Most expensive medical devices are only available to hospitals with funding to buy them. ShiftLabs builds cheaper devices designed for the nurses and medical practitioners who will use them, starting with infusion pumps. Most medical pumps cost in the $10,000 range. DripAssist is the $300 equivalent infusion pump. It has filed an FDA application and is shipping now. It has already had $1 million orders and $10 million in pilot programs.
Valor Water AnalyticsWater Utility Analytics. We are saving more water now than ever thanks to water conservation efforts, but utilities are now losing revenue because of it. Valor Water Analytics helps utilities save lost revenue. Utilities don’t know which customers are wasting water or saving. Valor helps utilities assess who is using water efficiently and who isn’t. It has already helped the state of North Carolina save over $10 million in revenue. It has booked half a million in recurring revenue and is selling to some of the largest water utilities in the world.
InstavestCollaborative Investing. People want to learn how to invest from the world’s best investors and Instavest helps investors share their how they do it. It does this by letting anyone follow a trade and share purchases in the stock market. It launched two weeks ago with 175 investors with $1.2 million under management with the aim to be the discount brokerage “killer.” The growth strategy includes attracting active investors on sites like SeekingAlpha. Every investor brings in another 3 investors, according to the company.
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Open ListingsSelf-Service Real Estate. Over 67% of homes are sold to repeat buyers who are already familiar with the process. The Open Listings platform eliminates the need for the real estate agent by providing the paperwork and giving the buyer the 3% fee they’d normally give to a real estate agent.
CloudMedx – Palantir For Healthcare. Collects patient data from different hospital sources in real-time to generate meaningful insights for better patient care. It aims to identify gaps in care with at risk patients to provide early detection using collaborative data. It has signed 15 organization giving them an annual revenue of $1.5 million.
BankJoyMobile Banking For Credit Unions. There are 6,000 credit unions in the U.S. They offer lower interest rates on loans and are community supported. However, they don’t always have the kinds of resources banks do to build mobile apps. For $1 per user per month, BankJoy provides credit unions with mobile services. Currently, BankJoy has 250,00 users and an $4.5 million annual revenue runrate.
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TransitmixSoftware To Run Cities. Major cities still use paper to route bus systems. Transitmix provides city planners with software that helps route the transportation system. It has signed contracts with 20 major cities in the U.S. and Canada. The software works with any city in the world by using demographic data and cost analysis to help cities make better decisions. It has a 60 day sales cycle with a $1 million run rate. The company says it has a $4 billion opportunity to build the software to run cities.
Zenflow – Medical Device For Enlarged Prostate. Many men will suffer from an enlarged prostate at some point in their life. Zenflow Spring is a device that props open the prostate and helps to relieve urine flow problems. This is a $5 billion opportunity in the U.S. and a $40 billion global opportunity. Thanks to a team that understands the FDA approval process and has a track record of other proven medical devices, its Spring device will be commercial by 2016.
FinalSecure Credit Card. A stolen card number can be used everywhere until it is shut down. Final aims to solve this problem by providing a credit card that has a unique number for every merchant. It works with an EMV based credit card that creates multiple numbers. The startup has already raised $1 million and says it has 37,000 potential customers signed up on the wait list. Applications will be open in a month.
LullyDevice To Fix Sleep. Six million children wake up in the middle of the night. Lully provides an under the mattress device to get kids to sleep through the night using buzzing and other tested techniques. It has handled over 8,000 nights of testing for night terrors to get the technology right and has sold out of 100 beta units, with 25% of sales coming from word-of-mouth. The device costs $169 and aims to help the whole family rest better at night.
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SpireWearable Breathing Tracker. Respiration fluctuations are a key signal of health problems, but they’re tough to monitor. Spire has developed a low-cost, accurate respiration sensor, and the infrastructure to turn data into health recommendations. It wants to give early warnings about big health problems and build its sensors into everyday objects and clothing. For now, its wearable can let you know if you’re stressed or have been sitting too long.

AnalyticsMDAir Traffic Control For Healthcare. Inefficiencies in how hospitals manage resources lead to huge wastes of money.  An empty operating room costs $5000 per hour, despite a long-waiting list of people needing surgery. AnalyticsMD uses machine learning to monitor, predict, and optimize how hospitals work.

SmarkingEnterprise SaaS For Parking. Companies in the parking market price their services and staff purely based on intuition, leaving money on the market. Smarking’s system lets them accurately track supply and demand so parking lots can optimize their businesses and boost revenue. While it might seem boring, parking is a massive market with no modern analytics infrastructure.

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20nProducing Valuable Chemicals From Genetically Modified Organisms. Pharmaceutical companies spend huge sums producing specialty chemicals. 20^n uses software to predict what genes can be used to genetically modify organisms so they naturally produce these valuable chemicals. It’s already invented a way to produce acetaminophen, the active ingredient in Tylenol. It’s also figured out a way to decrease one valuable chemicals price by 2 million times. 20^n now has over $1.7 million in contracts from DARPA and a massive cosmetics company, and is eyeing a wide array of chemicals for production.

GrubMarketOnline Farmer’s Market. GrubMarket provides on an online marketplace where consumers can buy food straight from farmers. GrubMarket then picks up the food and delivers it. By cutting out the wholesalers, distributors, and grocers, GrubMarket can take a big margin while making food cheaper and paying farmers more.

CribSpotCollege Rental Marketplace. It’s tough for students to manage the college housing rental process, as listings are fragmented across sites, and rentals require paper leases and handwritten checks. CribSpot aggregates the best college rentals, and lets students pay for them directly through the site. By charging a small fee to help students find and book rentals (something landlords sometimes do already), CribSpot plans to grab a chunk of the $25 billion US student housing rental market.

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KickPayA Marketplace For Buying And Selling Invoices. It takes the average invoice 48 days to get paid, depriving businesses of the cash they need to operate. KickPay lets individual investors buy up these invoices at a slight discount, getting businesses capital instantly. Investors see liquidity within two months and can make a double-digit percentage return. The market for KickPay is already huge, with $300 billion in invoices bought each year through a terrible interface full of contracts and paperwork.

Notable LabsPersonalized Cancer Treatment. Drug combinations have been very successful in fighting disease, but there are too many possible combinations to test on any single patient. Notable Labs instead takes a sample of a patient’s tumor to their lab, runs drug combination experiments to find out what works, and gives a report back to the patient’s doctor. This exposes it to no FDA risk, and cuts out big pharma companies that sell patented drugs.

Pretty Instant – On-Demand Event Photography. Pretty Instant can get you an event photographer in under 24 hours. Its technology can identify who is in a photo and send it to them so they share it, getting both the client and Pretty Instant more impressions that turn into inbound sales leads.

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VetProntoOn-demand Veterinarian House Calls. Pets and their owners hate going to the vet’s office. But VetPronto can make getting healthcare for pets both easier and cheaper by bringing the veterinarian to the sick pet’s home. This eliminates overhead and scheduling costs, while letting your furry best friend stay put.

Akido LabsA Standard API For Healthcare. Akido Labs wants to unlock health care data the way Clever unlocked educational data. It sells to hospital vendors that normally have to create endless custom integrations for each hospital’s backwards system. Akido sits between the two, standardizing the data coming out of the hospitals so its easy to build on for the vendors. Akido’s technology could make building medical software cheaper and easier, creating a platform that brings better health to everyone.

DroneBase – On-Demand Drone Services. Customers push a button, and DroneBase dispatches a local drone pilot with their own drone to come capture imagery, video, maps, and analysis for any project, like construction or infrastructure management. This lets big commercial clients avoid buying drones, employing pilots, or paying suppliers. DroneBase’s service can significantly undercut satellites, planes, and helicopters, while getting companies better data faster.

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MashGin – Self-Checkout Via Machine Vision. MashGin’s brick-and-mortar checkout kiosk uses cameras to machine vision scan objects and instantly ring them up. You just put your items, like and apple or a can of soda, into the kiosk that looks like a MakerBot box with no maker inside. It recognizes what they look like without user input or bar codes, and you can swipe your card to pay and leave. MashGin’s two-person team from Facebook and Bell Labs could change any business that relies on human vision. And it’s just received a letter of intent for $50 million a month of services from a major retailer.

Labdoor – Quality-Tested Online Marketplace For Supplements. The FDA doesn’t test supplements, and Labdoor says 79% of supplements fail quality control. Labdoor does its own testing so it can tell you what’s actually in Centrum or Muscle Milk even if the labels are wrong. The startup believes that user reviews aren’t enough to convince people what health products to buy, so it wants to be the quality control for everything important.

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Labdoor’s supplement marketplace

Bonfire – Full-Service Request For Proposal Management – $3 trillion is spent each year through  the Request For Proposal (RFP) system. When a business needs to buy something that costs over $50,000 they get RFP bids from potential supplies, and have to decide which to go with. That clumsy comparison process can take months. Bonfire manages all the RFPs for a business, determining which offer is best, and informing the buyer. Bonfire is currently selling its service for $5,000 a year to large companies and governments, but envisions an even bigger business in intelligence about what buyers and suppliers should do based on the data it gleams.

EquipmentShareAirbnb for Construction Equipment. Trillions of dollars of construction equipment sits idle all the time. 75% at any given time. EquipmentShare lets contractors rent out their idle equipment, and the startup keeps 20%. It can undercut traditional equipment renters by 30% where contractors spend an average of $900,000 a year. EquipmentShare could make it more affordable for smaller independent contractors to buy or rent the equipment they need, and help them create sustainable side businesses renting their cherry-pickers and cement-mixers.